Significance of measuring serum concentrations of remnant lipoproteins and apolipoprotein B-48 in fasting period.

Aim: To characterize lipid profiles conveniently in the fasting period to detect postprandial hyperlipidemic subjects, we measured the concentrations of lipids, including remnant lipoproteins and apoB-48, before and after loading the test meal in 24 normolipidemic subjects.

Methods: We examined remnant-like particle-cholesterol and -triglyceride (RLP-C, RLP-TG) by the immune adsorption method, RemL-C by the newly developed homogeneous method, and apoB-48 by chemiluminescence enzyme immunoassay.

Results: After loading, TG, RemL-C, RLP-C, RLP-TG, and apoB-48 concentrations were elevated.