Publications by authors named "Shihao Yu"
Article Synopsis
- Non-small cell lung cancer (NSCLC) shows poor response to traditional therapies, leading researchers to explore the impact of MHC I expression on immunotherapy effectiveness.
- Low-dose Suberoylanilide hydroxamic acid (SAHA), an HDAC inhibitor, was found to enhance CD8 T cell activity by increasing MHC I levels in NSCLC cells without harming cell viability.
- The study demonstrated that high MHC I levels stimulated specific CD8 T cells, improving their activation and antitumor effects, implicating potential strategies for NSCLC treatment enhancement through IFI modulation.
Background: Human brucellosis continues to be a great threat to human health in China. The present study aimed to investigate the spatiotemporal distribution of human brucellosis in China from 2004 to 2019, to analyze the socioeconomic factors, meteorological factors and seasonal effect affecting human brucellosis incidence in different geographical regions with the help of spatial panel model, and to provide a scientific basis for local health authorities to improve the prevention of human brucellosis.
Methods: The monthly reported number and incidence of human brucellosis in China from January 2004 to December 2019 were obtained from the Data Center for China Public Health Science.
For commercial aquatic animals, hypoxia phenomenon often occurs in live transport and aquaculture. In previous studies, much interest has been focused on antioxidant enzyme activities and could not present the complexities. The multifaceted responses, especially considering physiological indexes, histological structure, cell apoptosis, and immune pathways, are still unknown.
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