The impact of digital healthcare systems on pain and body function in patients with knee joint pain: a systematic review and meta-analysis.

The digital healthcare (DH) system has recently emerged as an advanced rehabilitation approach that promotes rehabilitation training based on virtual reality (VR) and augmented reality (AR). The purpose of this meta-analysis study is to review and assess the impact of DH systems on pain and physical function among patients diagnosed with knee joint pain. Between January 2003 and September 2023, studies that met the listed inclusion criteria were gathered from Scopus, PubMed, Web of Science, and EBSCO databases.

The Effects of Combined Exercise with Citrulline Supplementation on Body Composition and Lower Limb Function of Overweight Older Adults: A Systematic Review and Meta-Analysis.

The combined exercise with citrulline (CIT) supplementation is a potential adjuvant treatment approach to address the declining body composition and lower limb function of overweight older adults. However, research on this approach is limited. Thus, this study performed a meta-analysis review to explore the effects of combined exercise with CIT supplementation on body composition and lower limb function among overweight older adults.

Novel tripeptide RKH derived from protects against lethal sepsis.

Objective: The pathogenesis of sepsis is complex, and the sepsis-induced systemic proinflammatory phase is one of the key drivers of organ failure and consequent mortality. (AKK) is recognised as a functional probiotic strain that exerts beneficial effects on the progression of many diseases; however, whether AKK participates in sepsis pathogenesis is still unclear. Here, we evaluated the potential contribution of AKK to lethal sepsis development.

Effect of high-intensity interval training on aerobic capacity and fatigue among patients with prostate cancer: a meta-analysis.

Objective: This study focused on evaluating whether high-intensity interval training (HIIT) had an effect on aerobic capacity and fatigue among patients with prostate cancer (PCa) and exploring its effect on the immune system of PCa patients.

Methods: To investigate the potential effect of HIIT on patients with prostate cancer, a meta-analysis was carried out. From January 2012 to August 2022, studies that met predefined criteria were searched in the Scopus, PubMed, Web of Science, and EBSCO databases.

A critical review on retaining antibiotics in liquid digestate: Potential risk and removal technologies.

Substantial levels of antibiotics remain in liquid digestate, posing a significant threat to human safety and the environment. A comprehensive assessment of residual antibiotics in liquid digestate and related removal technologies is required. To this end, this review first evaluates the potential risks of the residual antibiotics in liquid digestate by describing various anaerobic digestion processes and their half-lives in the environment.

Properties and Roles of γδT Cells in NSM Infected C57BL/6 Mice.

Background: Many kinds of immune cells are involved in malaria infection. γδT cells represent a special type of immune cell between natural and adaptive immune cells that play critical roles in anti-parasite infection.

Methods: In this study, malaria infection model was constructed.

TLR7 modulating B-cell immune responses in the spleen of C57BL/6 mice infected with Schistosoma japonicum.

B cells played an important role in Schistosoma infection-induced diseases. TLR7 is an intracellular member of the innate immune receptor. The role of TLR7 on B cells mediated immune response is still unclear.

Ikzf2 Regulates the Development of ICOS Th Cells to Mediate Immune Response in the Spleen of -Infected C57BL/6 Mice.

Background: Th cells (helper T cells) have multiple functions in () infection. Inducible co-stimulator (ICOS) is induced and expressed in activated T lymphocytes, which enhances the development of B cells and antibody production through the ICOS/ICOSL pathway. It remains unclear about the role and possible regulating mechanism of ICOS Th cells in the spleen of -infected C57BL/6 mice.

Interferon Regulatory Factor 4 Regulates the Development of Polymorphonuclear Myeloid-Derived Suppressor Cells Through the Transcription of c-Myc in Cancer.

The accumulation of myeloid-derived suppressor cells (MDSCs) is one of the major obstacles to achieve an appropriate anti-tumor immune response and successful tumor immunotherapy. MDSCs in tumor-bearing hosts are primarily polymorphonuclear (PMN-MDSCs). However, the mechanisms regulating the development of MDSCs remain poorly understood.

Characterization of γδT cells in lung of Plasmodium yoelii-infected C57BL/6 mice.

Background: Malaria has high morbidity and mortality rates in some parts of tropical and subtropical countries. Besides respiratory and metabolic function, lung plays a role in immune system. γδT cells have multiple functions in producing cytokines and chemokines, regulating the immune response by interacting with other cells.

Adjustments of γδ T Cells in the Lung of -Infected C56BL/6 Mice.

Many kinds of lymphocytes are involved in () infection-induced disease. γδ T cells comprise a small number of innate lymphocytes that quickly respond to foreign materials. In this study, the role of γδ T cells in the lung of -infected C56BL/6 mice was investigated.

TLR7 Modulated T Cell Response in the Mesenteric Lymph Node of -Infected C57BL/6 Mice.

Toll-like receptors (TLRs) play an important role in regulating immune responses during pathogen infection. However, roles of TLRs on T cells reside in the mesenteric lymph node (MLN) were not be fully elucidated in the course of infection. In this study, T lymphocytes from the mesenteric lymph node (MLN) of -infected mice were isolated and the expression and roles of TLR2, TLR3, TLR4, and TLR7 on both CD4 and CD8 T cells were compared.

Changes of CD103-expressing pulmonary CD4 and CD8 T cells in S. japonicum infected C57BL/6 mice.

Background: Recent studies have shown that CD103 is an important marker for tissue-resident memory T cells (TRM) which plays an important role in anti-infection. However, the role of CD103 TRM was not elucidated in the progress of S. japonicum infection induced disease.

Infection Promotes the Response of Tfh Cells Through Down-Regulation of Caspase-3-Mediating Apoptosis.

CD4 T follicular helper (Tfh) cells, a new subset of immune cells, have been demonstrated to be involved in granulomatous responses to infection. However, the role and underlying mechanisms of Tfh cell aggregation in infection remain incompletely understood. In this study, we provide evidence that infection enhances the accumulation of Tfh cells in the spleen, lymph nodes, and peripheral blood of C57BL/6 mice.