Atopic dermatitis (AD) is a chronic skin disease linked to an overactive immune response, with potential connections to circadian rhythm disruptions that are still not fully understood.
Research involved analyzing RNA-sequencing data from AD patients to assess gene expression related to circadian rhythms and immune cell types.
Results showed that circadian rhythm genes were less active in AD, with increased levels of dendritic cells correlating negatively with these genes, highlighting the role of circadian rhythms in the disease's progression.