Publications by authors named "Shih-Hao Cheng"

Article Synopsis
  • The study aimed to evaluate the cardiovascular safety of romosozumab, a treatment for osteoporosis in postmenopausal women, amid concerns over its potential cardiovascular risks.
  • A systematic review identified 25 randomized controlled trials involving almost 25,000 participants, concluding that romosozumab does not significantly increase cardiovascular mortality or major cardiovascular events compared to placebo.
  • The findings suggest that romosozumab may be a safer treatment option than previously thought, but more real-world data are needed to fully validate this safety profile.
View Article and Find Full Text PDF

Spinal endoscopy has evolved significantly since its inception, offering minimally invasive solutions for various spinal pathologies. This study introduces a promising innovation in spinal endoscopy-a single-use digital endoscope designed to overcome the drawbacks of traditional optic endoscopes. Traditional endoscopes, despite their utility, present challenges such as fragility, complex disinfection processes, weight issues, and susceptibility to mechanical malfunctions.

View Article and Find Full Text PDF

Symptomatic osteoporotic compression fractures are commonly addressed through vertebroplasty and kyphoplasty. However, cement leakage poses a significant risk of neurological damage. We introduced "aspiration percutaneous kyphoplasty", also known as "decompressed kyphoplasty", as a method to mitigate cement leakage and conducted a comparative analysis with high viscosity cement vertebroplasty.

View Article and Find Full Text PDF

Osteoporosis-induced vertebral compression fracture (OVCF) occurs commonly in people over the age of 50, especially among menopausal women. Besides conservative therapy, minimally invasive percutaneous vertebroplasty (PVP) and kyphoplasty (PKP) have been widely used in clinical treatment and achieved good efficacy. However, the leakage of bone cement (CL) during vertebroplasty (PV) is a major risk that can cause (serious) complications such as compression of the spinal cord, pulmonary embolism, or even paraplegia.

View Article and Find Full Text PDF

Sarcopenia is a disease of gradual loss of muscle mass in elderly people, and the most common treatment options include nutritional supplementation and exercise. Vitamin D has potential beneficial effects for skeletal muscle tissue and has often been included in nutritional therapy formulations. However, the therapeutic effect of vitamin D for the treatment of sarcopenia has not yet been determine and there is a lack of high-quality supporting evidence.

View Article and Find Full Text PDF

This paper proposes a method for estimating the effective zone, including effective depth and effective range of compaction degree, from rapid impact compaction (RIC) on sand layer whose fines content is less than 10%. The proposed method utilizes a string of microelectromechanical system accelerometers to monitor the acceleration at various depths and propagation distances during compaction. To interpret and extract useful information from monitored data, peak-over-threshold (POT) processing and normal distribution function were used to analyze the recorded acceleration.

View Article and Find Full Text PDF

Study Design: Network meta-analysis of randomized controlled trials.

Objectives: Lumbar spondylolisthesis is a common indication for spinal fusion. Lumbar interbody fusion (LIF) is popular method to achieve arthrodesis, but previous syntheses usually used head-to-head comparison of 2 surgical methods, and no of them pooled analysis with high-quality.

View Article and Find Full Text PDF

Background: Giving patients anti-osteoporotic agents peri-operatively is a well-accepted strategy to increase fusion rate and prevent complications. The purpose of this study was to investigate effectiveness of teriparatide and bisphosphonate on fusion surgery of thoracic and lumbar spine.

Methods: We searched EMBASE and PubMed for randomized clinical trials (RCTs) and prospective comparative studies using teriparatide or bisphosphonate in peri-operative spinal fusion surgery.

View Article and Find Full Text PDF

Study Design: A network meta-analysis.

Objectives: Lumbar degenerative disc disease (LDDD) is an important issue in aging population, for which lumbar interbody fusion (LIF) is a feasible management in cases refractory to conservative therapy. There are various techniques available to perform LIF, including posterior (PLIF), transforaminal (TLIF), and anterior (ALIF) approaches.

View Article and Find Full Text PDF

Introduction: Hip fractures can be divided into intra-capsular and extra-capsular fracture based on fracture location; these two types of fracture have different pathogeneses, treatments and prognoses. Many factors influence the patterns of hip fractures, including the injury mechanism, areal bone mineral density and the geometry of the hip. However, the relationship between body composition and hip fracture pattern has not yet been discussed.

View Article and Find Full Text PDF

Photodetectors with ultrahigh sensitivity based on the composite made with all carbon-based materials consisting of graphite quantum dots (QDs), and two dimensional graphene crystal have been demonstrated. Under light illumination, remarkably, a photocurrent responsivity up to 4 × 10(7) AW(-1) can be obtained. The underlying mechanism is attributed to the spatial separation of photogenerated electrons and holes due to the charge transfer caused by the appropriate band alignment across the interface between graphite QDs and graphene.

View Article and Find Full Text PDF

We report the discovery of an enhancement of the random laser action in a nanocomposite comprising reduced graphene oxide nanoflakes and ZnO nanorods. We show that both emission intensity and lasing threshold exhibit an obvious improvement. Based on our theoretical calculations, the mechanism underlying the enhanced stimulated emission can be attributed to coupling between the optical transition and the surface plasmon resonance of the reduced graphene oxide nanoflakes, induced by the ZnO nanorod surface roughness.

View Article and Find Full Text PDF

We report the discovery of an enhancement of the random laser action in a nanocomposite comprising reduced graphene oxide nanoflakes and ZnO nanorods. We show that both emission intensity and lasing threshold exhibit an obvious improvement. Based on our theoretical calculations, the mechanism underlying the enhanced stimulated emission can be attributed to coupling between the optical transition and the surface plasmon resonance of the reduced graphene oxide nanoflakes, induced by the ZnO nanorod surface roughness.

View Article and Find Full Text PDF

A 67-year-old man was examined for persistent pain over his lower abdomen and was found to have a large pelvic tumor. During surgery, we detected a 16 × 9 × 9 cm(3) urinary bladder tumor with small intestinal adhesions, and performed partial cystectomy and segmental resection. Histological and immunohistochemical examinations established the diagnosis of malignant solitary fibrous tumor (SFT).

View Article and Find Full Text PDF

Based on the composite consisting of ZnO nanorods (NRs) grown on InGaN/GaN multiple quantum wells (MQWs), we have demonstrated a novel light-emitting device (LED) that has the capability to emit dual beam radiations. Interestingly, the relative intensity between the dual emissions is able to be manipulated by their polarizations. The underlying mechanism can be well understood in terms of the anisotropic optical properties arising from the geometric structures of constituent nanoscale materials.

View Article and Find Full Text PDF