Direct mapping from PET coincidence data to proton-dose and positron activity using a deep learning approach.

. Obtaining the intrinsic dose distributions in particle therapy is a challenging problem that needs to be addressed by imaging algorithms to take advantage of secondary particle detectors. In this work, we investigate the utility of deep learning methods for achieving direct mapping from detector data to the intrinsic dose distribution.

Xiao-Qing-Long-Tang attenuates allergic airway inflammation and remodeling in repetitive Dermatogoides pteronyssinus challenged chronic asthmatic mice model.

Ethnopharmacological Relevance: Xiao-Qing-Long-Tang (XQLT) has been used for centuries in Asia to effectively treat patients with bronchial asthma.

Aim Of The Study: We previously found that single and multiple doses of XQLT administered to sensitized mice before allergen challenge resulted in suppressed airway hyper-responsiveness and airway inflammation. In this study we aimed to investigate whether XQLT has the potential to attenuate the severity of asthma symptoms, and immunomodulatory mechanism of XQLT in a repetitive Dermatogoides pteronyssinus (D.

Comparison of a Chinese Herbal Medicine (CCH1) and Lactulose as First-Line Treatment of Constipation in Long-Term Care: A Randomized, Double-Blind, Double-Dummy, and Placebo-Controlled Trial.

Many institutionalized patients and their healthcare providers are dissatisfied with current laxative therapy. This study compared therapeutic efficacy, safety, and laxative cost of an herbal formula (CCH1) and lactulose for long stay patients with constipation. In this double-blind, double-dummy, and placebo-controlled trial, we randomized 93 residents with chronic constipation from two long-term care facilities in Taiwan to receive either CCH1 with lactulose placebo or CCH1 placebo with lactulose for 8 weeks, then followed up for 4 weeks without study medication.

Treatment of constipation in long-term care with Chinese herbal formula: a randomized, double-blind placebo-controlled trial.

Objectives: This study is aimed to evaluate the therapeutic efficacy and safety of CCH1, modified from an ancient herbal formula in Traditional Chinese Medicine, for the residents with constipation in long-term care.

Methods: In this randomized, double-blind, placebo-controlled trial, 90 residents from three long-term care units were randomized to 8 weeks of treatment with CCH1 or placebo and then the subjects were followed up for an additional 4 weeks.

Results: The mean numbers of weekly spontaneous bowel movement in the CCH1 group were greater than in the placebo group during the treatment phase of 8 weeks (p < 0.

Evaluation of ⁶⁰Co-gamma radiosterilization on Chinese medicines with HPLC/FTIR.

The aim of this study was to evaluate the effect of radiosterilization on 30 Chinese medicines using γ-rays from the isotope ⁶⁰Co. Two groups of Chinese medicines, non-treated and dry samples, were treated using a ⁶⁰Co irradiation source at the doses 0, 3, 6 and 9  kGy. After storage for 3 months, characterizations of chemical compounds and functional groups were performed by high-performance liquid chromatography (HPLC) and Fourier transform infrared spectroscopy.

Prophylaxis of experimentally induced calcium oxalate nephrolithiasis in rats by Zhulingtang, a traditional Chinese herbal formula.

Background: Zhulingtang (ZLT), a traditional Chinese medicine formula, was used to evaluate the antilithic effects of experimentally induced calcium oxalate (CaOx) nephrolithiasis in ethylene glycol (EG)-fed rats.

Materials And Methods: A total of 35 male Sprague-Dawley rats were randomly divided into 4 groups. Rats in group 1 (n = 8) served as the normal control.

The evaluation of reno- and hepatoprotective effects of huai-shan-yao (Rhizome Dioscoreae).

Huai-shan-yao (Chinese yam; Rhizome Dioscoreae) is a common food in China. In the present study, we evaluated the protective effects of the crude extract of huai-shan-yao on acute kidney and liver injuries in rats induced by ethanol. Results of pharmacological, biochemical and pathologic observations all showed that rats treated with the extract of huai-shan-yao had decreased damage in renal tubules as well as decreased inflammation in the central vein and necrosis in the liver tissue.

Effects of "Chinese yam" on hepato-nephrotoxicity of acetaminophen in rats.

Aim: To study the effect of yam in Taiwan, which is a commonly used Chinese medicine, on hepato-nephro-toxicity in rats.

Methods: Crude water extract of yam (Dioscorea alata L), was used to treat rats with an acute toxicity induced by acetaminophen (APAP) challenge.

Results: The pharmacological and biochemical studies showed the extract of yam had the effect of kidney secureness and liver fortification (P < 0.