Purpose: We report two cases of Vogt-Koyanagi-Harada disease (VKH) in which shallow anterior chambers were improved after steroid pulse therapy.
Case: The patients were women aged 65 and 72. They had headaches, decreased visual acuity and shallow anterior chamber in both eyes.
Graefes Arch Clin Exp Ophthalmol
March 2015
Purpose: To evaluate the short-term efficacy of aflibercept monotherapy for patients with treatment-naïve polypoidal choroidal vasculopathy (PCV).
Design: Prospective, consecutive case series.
Methods: Thirty-three consecutive eyes of 33 symptomatic PCV patients (17 men, 16 women, mean age 75 ± 8.
Purpose: To report clinical findings of three patients with unilateral peculiar choroidal excavation in the macula detected by spectral-domain (SD) optical coherence tomography (OCT).
Methods: Three cases with unilateral choroidal excavation in the macula detected by SD OCT. Fluorescein angiography (FA), indocyanine green angiography (IA), ultrasonography, visual field tests and multifocal electroretinography (mfERG) were performed.
Takayasu disease was first reported in 1908 by Mikito Takayasu as "a case of peculiar changes in the central retinal vessels." Because in these patients the pulse of the radial artery is impalpable, investigations focusing on the ischemic symptoms of the upper body were conducted. In 1948, Shimizu and Sano named this pathological condition "pulseless disease.
View Article and Find Full Text PDFPurpose: To evaluate how sutureless amniotic membrane patches may affect visual functions in normal human eyes.
Design: Prospective intervention study.
Methods: Ten sets of sutureless amniotic membrane patch manufactured as PROKERA were inserted in one eye of six normal patients.
Purpose: To measure the light transmission properties of human limbal epithelial cell sheets (LECSs) cultured on human amniotic membranes (AMs) and compare them with those of AMs with and without amniotic epithelium.
Methods: Total light transmission of 3 kinds of tissue (LECSs, intact AMs, denuded AMs) was measured in the 250- to 800-nm range by using a spectrophotometer.
Results: The percent transmission of each kind of tissue decreased gradually and continually throughout the spectrum as the wavelength shortened and dropped rapidly at 300 nm to less than 20% at 250 nm.
Purpose: To measure the light transmission of human amniotic membrane (AM) and compare it with that of therapeutic soft contact lens (TSCL).
Methods: Total light transmittance of each sample (4 AMs and 2 TSCLs) was measured in the 250- to 800-nm range by using a spectrophotometer.
Results: The percent light transmission of TSCL was nearly 100% at wavelengths greater than 450 nm, decreased gradually in the sub-450-nm range, and reached 78.
Purpose: To present an unusual case in which the honeycomb opacities of Thiel-Behnke corneal dystrophy disappeared during a course of chronic Thygeson superficial punctate keratitis.
Case: A 29-year-old woman with a 5-year history of decreased visual acuity in both eyes had bilateral honeycomb-shaped corneal opacities, located mainly in the superficial central cornea. She was diagnosed as having Thiel-Behnke corneal dystrophy, which we confirmed genetically.
Purpose: To demonstrate the usefulness of fluorescein dye to detect a corneal epithelial defect through an amniotic membrane patch in 4 cases.
Patients And Method: Two patients with painful bullous keratopathy, 1 patient with total limbal deficiency, and 1 patient with acute chemical burn underwent surgeries in conjunction with amniotic membrane as patch. Postoperatively, slit-lamp biomicroscopic examination with and without fluorescein staining was performed.