Radiofrequency ablation combined with transarterial chemoembolization for intermediate hepatocellular carcinoma.

Aim: Radiofrequency ablation therapy (RFA) combined with transarterial chemoembolization (TACE) (combination therapy) is effective for early-stage hepatocellular carcinoma (HCC). The aim of this study was to compare the long-term effects of combination therapy with supportive care alone for intermediate HCC.

Methods: The study included 58 patients with intermediate HCC who received combination therapy (n = 34) or supportive care alone (n = 24).