[Prospective study of extended versus limited lymphadenectomy in patients undergoing radical prostatectomy with localized prostate cancer].

Patients undergoing radical prostatectomy at our hospital from January 1995 until March 2008 were subjected to limited lymphadenectomy involving only the obturator nerve lymph node. In contrast to published reports, of 488 biopsies, we encountered only three cases of lymph node metastasis. Therefore, starting in April 2008, we conducted a prospective study of limited versus extended lymphadenectomy, the latter involving the obturator fossa and internal iliac lymph nodes.

Pathological characteristics and clinical course of bladder tumour developing after nephroureterectomy.

Objectives: To determine the pathological features and clinical course of intravesical recurrence after nephroureterectomy (NU) for upper urinary tract (UUT) cancer.

Patients And Methods: Among 325 patients undergoing NU with bladder cuff excision for UUT cancer, in this retrospective multi-institutional study we evaluated 113 who developed bladder tumour after NU. Excluding patients with (i) perioperative systemic chemotherapy or radiotherapy for UUT cancer; (ii) a history of previous or synchronous bladder cancer at the time of NU; (iii) distant metastasis at the time of NU; (iv) a follow-up of <1 year after the initial bladder cancer recurrence; or (v) missing data, 74 patients were included in this study.

Role of lymph node density in predicting survival of patients with lymph node metastases after radical cystectomy: a multi-institutional study.

Objectives: To evaluate the prognostic role of different clinico-pathological parameters in node-positive patients treated by radical cystectomy.

Methods: A retrospective multi-institutional study of 435 patients who underwent radical cystectomy between 1990 and 2005 was carried out. Of them, pathological lymph node (LN) metastases were found in 83 patients.

The role of lymph-node dissection in the treatment of upper urinary tract cancer: a multi-institutional study.

Objectives: To determine the role of lymph-node (LN) dissection in patients undergoing surgery for upper urinary tract (UUT) cancer.

Patients And Methods: We reviewed the clinicopathological data from 312 patients with UUT cancer treated predominantly by nephroureterectomy. The relationship between clinical characteristics and cancer-specific survival (CSS) was analysed, focusing on node-related information.