Publications by authors named "Shigenori Takeda"
Article Synopsis
- The study introduces MS-DIAL 5, a software designed for analyzing complex mass spectrometry data to better understand lipid structures and localization, integrating a species-specific lipidome database for enhanced accuracy.* -
- With optimized settings, MS-DIAL 5 accurately identified lipid structures for 96.4% of tested standards and effectively assigned specific positions in lipids, particularly for complex molecules found in the eye.* -
- The research also identified an enzyme (glycerol 3-phosphate acyltransferase) linked to the incorporation of important fatty acids into lipids, using both mass spectrometry techniques and experimental validation.*
Ultrasensitive detection of nonlabelled bovine serum albumin is performed in micro/nanofluidic chips using a photothermal optical phase shift (POPS) detection system. Currently, micro- and nanofluidics allow the analysis of various single cells, and their targets of interest are shifting from nucleic acids to proteins. Previously, our group developed photothermal detection techniques for the sensitive detection of nonfluorescent molecules.
View Article and Find Full Text PDFBrain temperature in patients with chronic hydrocephalus after subarachnoid hemorrhage.
Neurol Med Chir (Tokyo)
January 2004
The relationships between temperature indices and clinical condition on admission or improvement after ventriculoperitoneal (VP) shunting were evaluated in patients with subarachnoid hemorrhage (SAH). Brain temperatures were measured at intervals of 1 cm from the brain surface to the lateral ventricle at shunt operation. Rectal temperature was also measured.
View Article and Find Full Text PDFThe previously reported three-dimensional stereotaxic region of interest (ROI) template (3DSRT-t) for the analysis of anatomically standardized technetium-99m-L,L-ethyl cysteinate dimer (99mTc-ECD) single photon emission computed tomography (SPECT) images was modified for use in a fully automated regional cerebral blood flow (rCBF) quantification software, 3DSRT, incorporating an anatomical standardization engine transplanted from statistical parametric mapping 99 and ROIs for quantification based on 3DSRT-t. Three-dimensional T2-weighted magnetic resonance images of 10 patients with localized infarcted areas were compared with the ROI contour of 3DSRT, and the positions of the central sulcus in the primary sensorimotor area were also estimated. All positions of the 20 lesions were in strict accordance with the ROI delineation of 3DSRT.
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