Publications by authors named "Shigekazu Takizawa"
Article Synopsis
- Flow cytometry is essential for analyzing cell populations but faces a "color barrier" limiting the number of detectable traits due to overlapping fluorescence signals.
- Researchers developed a new method called color-scalable flow cytometry using coherent Raman techniques to overcome this limitation, allowing for more simultaneous measurements.
- The study successfully used 12 different Raman tags to analyze breast cancer cells with high accuracy and demonstrated potential for detecting over 140 colors using a single laser setup.
A characteristic clinical feature of COVID-19 is the frequent incidence of microvascular thrombosis. In fact, COVID-19 autopsy reports have shown widespread thrombotic microangiopathy characterized by extensive diffuse microthrombi within peripheral capillaries and arterioles in lungs, hearts, and other organs, resulting in multiorgan failure. However, the underlying process of COVID-19-associated microvascular thrombosis remains elusive due to the lack of tools to statistically examine platelet aggregation (i.
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- Label-free particle analysis is important in various industries and sciences but typically has lower throughput compared to fluorescence methods.* -
- This study introduces a new label-free analyzer that uses dual-comb coherent Raman scattering spectroscopy, achieving a high scan rate of 10 kHz.* -
- The analyzer successfully measured polystyrene microparticles at a rate of over 1000 particles per second, making it suitable for precise statistical analysis of numerous microparticles, including biological cells.*