Publications by authors named "Shiflett J"

Objectives: This study aimed to report geographic and demographic patterns of patients with craniosynostosis (CS) treated at Children's of Mississippi, the state's only American Cleft Palate-Craniofacial Association-approved craniofacial team.

Methods: Patients with CS were treated at a tertiary pediatric hospital cared for by craniofacial surgeons and neurosurgeons from 2015 to 2020. Demographic, geographic, and CS diagnosis details, including sex, gestational age, race, ethnicity, insurance status, and affected cranial suture type(s), number, and associated syndromic diagnosis were collected, including birth county and total live births from state data.

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Posterior vault distraction osteogenesis (PVDO) has been shown to resolve acute intracranial hypertension (AIH) while carrying an acceptable perioperative morbidity profile. PVDO has been associated with symptomatic improvement and fewer surgeries in those requiring ventriculoperitoneal shunts. The authors' experience using PVDO as an acute intervention is presented, demonstrating its safety and efficacy for management of AIH.

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Rickets results from defective bone mineralization, leading to skeletal deformities. Among those deformities, rickets has been associated with craniosynostosis, the premature closure of cranial sutures. Most of these patients have fusion of major sutures.

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Article Synopsis
  • The treatment of multisuture craniosynostosis, especially in immunosuppressed organ transplant patients, presents unique challenges but can be effectively managed with cranial distraction osteogenesis.
  • Two case studies are discussed: a 3-year-old girl post-kidney transplant who had a complicated recovery after her surgery, and a 2-year-old boy post-heart transplant who experienced a lesser degree of complications.
  • Both patients successfully expanded their cranial vaults using this procedure, and follow-up care showed no signs of elevated intracranial pressure.
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Norrie disease is a genetic disorder of the retina characterized by impaired retinal vascular development leading to retinal detachment and blindness. Non-retinal manifestations of the disorder include intellectual disability and seizure disorders. However, to date, no association with neurological mass lesions has been described.

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Cerebral delayed ischemia due to arterial vasospasm is a rare complication following epilepsy surgery. Here we report the third known case and first of diffuse vasospasm. A 48-year-old woman underwent a transcortical anterior left temporal lobectomy.

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Atypical teratoid/rhabdoid tumors (AT/RT) are highly aggressive malignant primitive neoplasms that commonly occur in children younger than 2 years of age. The prognosis is generally dismal with a median survival time of <1 year. The majority of AT/RT occur in the posterior fossa and less frequently the supratentorium.

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Introduction: Arterial cerebral aneurysms in the neonatal population are rare, and while the association of interrupted aortic arch and intracranial aneurysm has been reported in the adult and pediatric population (three cases each), to date, it has not been reported in the neonate.

Case Report: We report the case of a 26-day-old girl who presented with a generalized seizure 2 weeks after undergoing congenital heart surgery. Head CT revealed diffuse SAH with a 1.

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Introduction: The increased incidence and success of strip craniectomy with postoperative helmet therapy in the treatment of sagittal craniosynostosis has been documented by multiple centers throughout the country and world. The authors report a child with a postoperative implantation intradiploic epidermoid cyst following a strip craniectomy, a complication, that to our knowledge, has not been reported.

Methods: This clinical report involves a 3-year-old boy with a scaphocephalic appearance who was transferred to our center following an interstate adoption.

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Article Synopsis
  • Diving Response (DR) is a survival mechanism present in all animals, allowing them to cope with low oxygen conditions, which was previously linked to neuroprotection in brain injury models in rats.
  • The study examines how cold stimulation of the forehead can trigger a physiological response similar to that of ammonia stimulation in the nasal cavity, both of which induce DR in rats.
  • Results indicate the forehead's cold stimulation may provide neuroprotective benefits without the direct involvement of the subthalamic vasodilator area, suggesting its potential for neuroprotective therapy.
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