Publications by authors named "Shifang Zhan"
Cadmium ions are considered one of the most dangerous heavy metal pollutants. The human body does not require cadmium for growth and development, yet continuous intake of cadmium ions due to environmental pollution can lead to their accumulation in the body. This accumulation can result in damage to the urinary system and, in severe cases, pose life-threatening risks.
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- This paper reviews the research on repairing heart injuries caused by acute myocardial infarction, emphasizing myocardial regeneration, cell death (apoptosis), and scarring (fibrosis).
- It highlights recent advances in stem cell transplantation and gene therapy, noting their importance in the recovery process of heart tissue.
- While progress has been made, there are still many challenges and unresolved problems that need more research in the field of heart injury repair.
Doxorubicin (Dox), a chemotherapeutic agent frequently used to treat cancer, elicits cardiotoxicity, a condition referred to as Dox-induced cardiotoxicity (DIC), and ferroptosis plays a contributory role in its pathophysiology. Fucoidan, a polysaccharide with various biological activities and safety profile, has potential therapeutic and pharmaceutical applications. This study aimed to investigate the protective effects and underlying mechanisms of fucoidan in DIC.
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