[Expression and significance of the cyclin E in laryngeal carcinomas].

Objective: To investigate the clinicopathological significance of the cyclin E expression in laryngeal squamous cell carcinomas (LSCCs).

Method: The expression of cyclin E was detected by immunohistochemistry method in 50 cases of LSCCs, 20 cases of dysplastic squamous epithelium and 10 polyps of vocal cord.

Result: The positive expression of cyclin E was localized in the nuclei of cells.

[The comparison of polymerase chain reaction and standard to fungi].

Objective: The aim of this study was to compare the sensitivity of conventional culture and PCR method.

Method: DNA samples were collected from the sinus of 20 patients with chronic sinusitis and 18 patients diagnosed as fungal sinusitis clinically. Fungal specific PCR analysis and standard culture were performed on every sample.

[Effects of anti-cancer bioactive peptide on cell cycle in human nasopharyngeal carcinoma strain CNE].

Objective: To investigate effects of two kinds of anti-cancer bioactive peptide (ACBP) on proliferation and cell cycle in human nasopharyngeal carcinoma strain CNE.

Methods: Cell culture was used in vitro, CNE cells were exposed to different concentration ACBP, in all groups, contrast groups were set up. And 24, 48, 72 hours later, growth characteristics of CNE cells were studied by morphological observation and MTT assay .

[Olfactory function and olfactory marker protein in patients with chronic sinusitis].

Objective: To study the pathogenesis of dysosphresia in patients with chronic sinusitis, to discuss the expression and significance of olfaction marker protein in olfactory mucosa.

Methods: There were 55 cases with chronic sinusitis in the experimental group, and 11 cases in the control. All of them were first tested by subjective method, and then the olfactory marker protein in olfactory mucosa was examined by the method of immunohistochemistry.

[Research of the P substance on the olfactory mucous in sinusitis].

Objective: To discuss the pathogenesis of dysosphresia in the chronic sinusitis patients.

Method: Fifty-five cases with chronic sinusitis as experimental group, and 11 cases as control,mere analyzed with acidophilus monitor, and then the P substances in their olfactory mucous were detected.

Result: The positive ratio is 50.