Publications by authors named "Shichu Liu"
Downward surface solar radiation (DSSR) is critical for the Earth system. It is well-known that DSSR over land has fluctuated on decadal timescales in the past. By utilizing a combination of station observations and the latest CMIP6 simulations, here we show that DSSR had a global consistent decline during 1959-2014, with comparable contributions from greenhouse gases (GHGs) and anthropogenic aerosols.
View Article and Find Full Text PDFMetabolic Characteristics of Sclera in Lens-Induced Myopic Guinea Pigs.
Invest Ophthalmol Vis Sci
November 2024
Article Synopsis
- Myopia in guinea pigs was induced using special lenses, and researchers investigated the metabolic changes in the sclera, focusing particularly on amino acid levels.
- Metabolomic analyses revealed significant alterations in metabolic pathways linked to myopia, highlighting reductions in specific amino acids in the affected sclera.
- Supplementing with glycine was found to counteract some effects of myopia, increasing collagen levels, inhibiting eye elongation, and reversing changes in certain proteins associated with this condition.
The sodium pump Na/K ATPase a1 subunit(NKA a1), an attractive cancer-related biomarker and therapeutic target, is closely related to the development and progression of several cancers including breast cancer. Currently, a NKA a1 inhibitor, UNBS1450, has already evidenced its great therapeutic potential in personalized cancer treatment. The ability of non-invasive imaging of NKA a1 expression would be useful for selecting cancer patients who may benefit from this drug.
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