Efficacy of Erbium:YAG Laser for Regenerative Surgical Treatment of Peri-implantitis: Clinical, Microbiological, and Biomarker Analyses.

This paper reports on a study undertaken to ascertain the efficacy of the erbium:YAG laser (EYL) for peri-implantitis treatment. A total of 12 patients with bone loss resulting from peri-implantitis were involved in this study. The treatment protocol consisted of using the EYL for implant surface debridement and deproteinized bovine bone mineral (DBBM) for bone grafting.

Effectiveness of an erbium-doped: yttrium, aluminum and garnet laser for treatment of peri-implant disease: Clinical, microbiological, and biochemical marker analyses.

Background: The effectiveness of an erbium-doped: yttrium, aluminum and garnet (Er: YAG) laser (EYL) for the treatment of peri-implant disease (PID) remains unclear. The aim of this study was to compare non-surgical EYL therapy for PID with locally delivered minocycline hydrochloride (MC) ointment therapy by evaluating clinical, microbiological, and biochemical markers.

Material And Methods: Thirty-seven patients with PID were randomly assigned to either the EYL group (n = 18) or the MC group (n = 19).

Prevalence and risk factors for peri-implant diseases in Japanese adult dental patients.

We investigated the prevalences and risk factors for peri-implant diseases in Japanese adult dental patients attending a follow-up visit at dental hospitals or clinics as part of their maintenance program. This cross-sectional multicenter study enrolled patients with dental implants who attended regular check-ups as part of a periodontal maintenance program during the period from October 2012 through September 2013. Patients with implants with at least 3 years of loading time were included in the study.

Osteoclast and osteoblast activities on carbonate apatite plates in cell cultures.

Previous studies have demonstrated that carbonate apatite (CA) is superior to hydroxyapatite (HA) and β-tricalciumphosphate (β-TCP) with regard to osteoclastic resorption, but evidence on osteoclast and osteoblast response remains controversial. In the present study, the expression of bone related mRNA is examined on CA, HA, β-TCP, and titanium plates. ICR mouse osteoblast cells are cocultured with ICR mouse bone marrow cells.

Induction of new bone by basic FGF-loaded porous carbonate apatite implants in femur defects in rats.

Objectives: The aim of the present study was to investigate whether porous carbonate apatite (CA) containing basic FGF (bFGF) enhances bone augmentation as compared with porous CA alone.

Material And Methods: Thirty-six disc-shaped porous CA implants were inserted into femur defects in 36 Wister rats. Porous CA containing 0, 5, or 50 ng of bFGF was placed in the defect.

Periodontal tissue regeneration using fibroblast growth factor-2: randomized controlled phase II clinical trial.

Background: The options for medical use of signaling molecules as stimulators of tissue regeneration are currently limited. Preclinical evidence suggests that fibroblast growth factor (FGF)-2 can promote periodontal regeneration. This study aimed to clarify the activity of FGF-2 in stimulating regeneration of periodontal tissue lost by periodontitis and to evaluate the safety of such stimulation.

Denture-handling ability of elderly persons with dementia: examination of time spent inserting and removing dentures.

To evaluate the effects of dementia on denture-handling ability, we measured the amount of time that elderly subjects spent inserting and removing dentures. Elderly subjects with dementia tended to take more time inserting and removing dentures than those who were not demented. Only elderly patients who were severely demented needed significantly more time removing partial dentures than they did removing complete dentures.