Unvaccinated Children Are an Important Link in the Transmission of SARS-CoV-2 Delta Variant (B1.617.2): Comparative Clinical Evidence From a Recent Community Surge.

Objective: To evaluate the necessity of Covid-19 vaccination in children aged < 12 y by comparing the clinical characteristics between unvaccinated children aged < 12 y and vaccinated patients aged ≥ 12y during the Delta surge (B.1.617.

Bioinformatics Analysis of Key micro-RNAs and mRNAs under the Hand, Foot, and Mouth Disease Virus Infection.

To clarify crucial key micro-RNAs and mRNAs associated with hand, foot, and mouth disease (HFMD) virus infection, we conducted this bioinformatics analysis from four GEO datasets. The following datasets were used for the analysis: GSE85829, GSE94551, GSE52780, and GSE45589. Differentially expressed genes (DEGs) were acquired, and the analysis of functional and pathway enrichment and the relative regulatory network were conducted.

[Genetic analysis of a male infant with Menkes disease].

Objective: To carry out genetic testing for a male infant suspected for Menkes disease.

Methods: Genomic DNA of the proband and his parents were extracted and subjected to family trio whole exome sequencing (WES). Microduplication and microdeletion of the ATP7A gene were detected by multiplex ligation-dependent probe amplification (MLPA).

Tanshinone IIA attenuates ovalbumin-induced airway inflammation and hyperresponsiveness in a murine model of asthma.

Objectives: Tanshinone IIA (T. IIA), one of the most pharmacologically active components extracted from , has anti-inflammatory and antioxidant features. The aim of the present study is to investigate the benefit of on asthma using a murine model of asthma induced by ovalbumin (OVA).

[A case report of EIF2AK3-related Wolcott-Rallison syndrome and literature review].

The patient was a female infant aged 1 month and 29 days. She was admitted to the hospital due to convulsions for 6 days and increased blood glucose level for 5 days. She had unstable blood glucose levels.

Surface enhancement of THz wave by coupling a subwavelength LiNbO slab waveguide with a composite antenna structure.

Highly intense terahertz electromagnetic field and efficiently surface localized terahertz field in subwavelength volumes are of vital importance for terahertz photonics integration, also will greatly accelerate the development for integrated applications in biochemical sensing, imaging, terahertz spectroscopy, enhancement of nonlinear effects and even quantum research. In this paper, we achieved large terahertz field enhancement and surface field localization through depositing a pair of Au composite antennas on a LiNbO subwavelength slab waveguide, which can serve as an excellent on-chip platform for terahertz research and application. The antennas consist of two opposing tip-to-tip triangles separated by a gap, and each triangle combines with a strip antenna.

[Changes in serum cortisol and adrenocorticotropic hormone in children with sepsis shock and their clinical significance].

Objective: To study the changes in serum levels of cortisol and adrenocorticotropic hormone (ACTH) in children with septic shock (SS) and to explore their relationship with the disease severity and prognosis.

Methods: Twenty-five children with decompensated SS and 24 children with early SS were enrolled. Serum cortisol and ACTH levels were determined on admission and days 3 and 8 after admission.

[Comparison of the risk factors for asthma in children between urban and rural areas in Fuzhou City].

Objective: To explore the prevalence and the different risk factors for asthma in children between urban and rural areas in Fuzhou, Fujian province.

Method: The epidemiological survey of asthma in 0-14 years old children was conducted from October 2009 to October 2010 between Fuzhou urban and rural areas in Fujian province. The investigation subjects were selected in urban and rural areas by phased stratified random cluster sampling.

[A clinical analysis of eight proven cases of pulmonary mucormycosis].

Objective: To improve the understanding of pulmonary mucormycosis by analyzing the clinical manifestations, imaging features, diagnosis, treatment and prognosis of this disease.

Methods: The clinical data of eight patients diagnosed as pulmonary mucormycosis by histopathologic examination were retrospectively analyzed.

Results: Eight patients included six males and two females with age from 36 days to 66 years.

[Clinical research of chloasma treated with the meridian cosmetology and the impacts on estrogen and progestin].

Objective: To observe the efficacy difference between meridian cosmetology and western medicine in the treatment of chloasma and explore the impacts of meridian cosmetology on E2 and PRGE.

Methods: Three hundreds cases of chloasma were randomized into a meridian cosmetology group and a western medication group according to the visit sequence, 150 cases in each one. In the meridian cosmetology group, the meridian regulation, acupuncture based on pattern/syndrome differentiation [at the body acupoints such as Qihai (CV 6), Xuehai (SP 10), Zusanli (ST 36), Sanyinjiao (SP 6), Ganshu (BL 18), Pishu (BL 20) and Shenshu (BL 23), etc.

[Observation on therapeutic effect of acupoint catgut-embedding combined western medicine for epilepsy of generalized seizures type].

Objective: To compare the efficacy differences between acupoint catgut-embedding combined western medicine (ACCWM) and simple western medicine (WM) for treatment of epilepsy of generalized seizures type.

Methods: Fifty-two patients with epilepsy of generalized seizures type were randomly divided into an ACCWM group (n=30) and a WM group (n=22). Dazhui (GV 14), Yaoshu (GV 2), Jiuwei (CV 15), Qihai (CV 6) were selected in the ACCWM group as the main acupoints combined with routine antiepileptic drugs, Valpromide was taken orally, 2.