Publications by authors named "Shiao-Fwu Tai"
(1) Background: The optimal cutoff value that maximizes the prognostic value of surgical margins in patients with resected oral cavity squamous cell carcinoma has not yet been identified. (2) Methods: Data for this study were retrieved from the Taiwan Cancer Registry Database. A total of 13,768 Taiwanese patients with oral cavity squamous cell carcinoma were identified and stratified according to different margin statuses (0, 0.
View Article and Find Full Text PDFBackground: The administration of postoperative radiotherapy remains controversial in pN1 oral cavity cancer patients without extranodal extension. The aim is to determine whether postoperative radiotherapy reduces the neck recurrence rate and improves the survival outcomes of pN1 patients.
Methods: This study consecutively enrolled 1056 patients with newly diagnosed oral squamous cell carcinoma who underwent tumor wide excision and neck dissection from September 2002 to November 2019.
Article Synopsis
- This study analyzed the impact of lymph node burden on survival outcomes in patients with oral cavity squamous cell carcinoma using a meta-analysis of 11 studies involving over 20,600 patients.
- Results indicated that a higher lymph node burden is linked to significantly worse overall survival, disease-specific survival, and disease-free survival, with specific cutoff values identified for the worst outcomes.
- The authors concluded that lymph node burden serves as a key prognostic factor for survival in this type of cancer but emphasized the need for further high-quality research to refine these cutoff values.
Background: Growing evidence indicates that measures of body composition may be related to clinical outcomes in patients with malignancies. The aim of this study was to investigate whether measures of regional adiposity-including subcutaneous adipose tissue index (SATI) and visceral adipose tissue index (VATI)-can be associated with overall survival (OS) in Taiwanese patients with bone metastases.
Methods: This is a retrospective analysis of prospectively collected data.
Article Synopsis
- Older patients with metastatic cancer tend to have higher neutrophil-to-lymphocyte ratios (NLR) and lower overall survival (OS) rates compared to younger patients.
- Research involving 3981 patients showed that a pretreatment NLR below the median is an independent indicator of better OS for both age groups.
- Specifically for older patients, those with a low NLR who received systemic therapy had the best survival outcomes.
Background: C-reactive protein (CRP) is an early marker for inflammation, and a relationship between serum CRP levels and survival in oral cancer has been demonstrated previously. In this study, we investigated the roles of CRP in different oral cancer subsites.
Methods: Three hundred and forty-three oral squamous cell carcinoma patients between June 1999 and March 2015 were retrospectively reviewed.