An implantable composite scaffold for amplified chemodynamic therapy and tissue regeneration.

Tissue regeneration and tumor cell killing after surgical resection are the two keys to achieving effective tumor therapy. In this study, an implantable system with combined functions of tumor therapy and tissue repair was constructed. Tannic acid (TA)/Fe nanoparticles with Fenton catalytic activity were loaded with GSH inhibitor BSO drug (BTF), and acted as the therapeutic factor to realize amplified chemodynamic tumor treatment.

A Volumetric Absorptive Microsampling UPLC-MS/MS Method for Simultaneous Quantification of Tacrolimus, Mycophenolic Acid and Creatinine in Whole Blood of Renal Transplant Recipients.

(1) Background: Continuous monitoring of tacrolimus (TAC), mycophenolic acid (MPA), and creatinine (Cre) after renal transplantation is vitally important. In this study, we developed a new method based on volumetric absorptive microsampling (VAMS) combined with Ultra Performance Liquid Chromatography−Tandem Mass Spectrometry (UPLC-MS/MS) to simultaneously quantify three analytes including TAC, MPA, and Cre in whole blood. (2) Methods: The VAMS-based UPLC-MS/MS assay used a shared extraction and a single injection to simultaneously quantify the included TAC, MPA, and Cre.

A Modularized IoT Monitoring System with Edge-Computing for Aquaponics.

Aquaponics is a green and efficient agricultural production model that combines aquaculture and vegetable cultivation. It is worth looking into optimizing the proportion of fish and plants to improve the quality and yield. However, there is little non-destructive monitoring of plant growth in aquaponics monitoring systems currently.

A Single Approach to Arthroscopic Reduction and Debridement for Developmental Dislocation of the Hip in 12 Infants.

BACKGROUND Developmental dislocation of the hip (DDH) results in osteoarthritis in infants and children. This study aimed to investigate the effects of a single approach to arthroscopic reduction and debridement on clinical outcome in 12 infants with DDH. MATERIAL AND METHODS Twelve infants with irreducible DDH underwent single approach arthroscopic reduction and debridement followed by the use of a frog-leg position plaster cast with fixed flexion and abduction of the hips combined with external fixation for 6-8 weeks.

Biomechanical analysis of pinning configurations for a supracondylar humerus fracture with coronal medial obliquity.

Despite hundreds of studies of pinning configurations for transverse supracondylar humerus fractures, very few studies have investigated the optimal pin configurations in the treatment of supracondylar humerus fractures with coronal medial obliquity. The aim of this study was to develop a model of supracondylar humerus fractures with coronal medial obliquity and compare the stability of three various pin configurations to provide an acceptable pin placement. Oblique cuts were made in synthetic humeri at the level of the coronoid and olecranon fossae to simulate a humeral supracondylar fracture with coronal medial obliquity.