A Patient With Hepatocellular Carcinoma and Lung Metastasis Successfully Underwent Curative Surgery Following the Downstaging Treatment: A Case Report.

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy. Hepatic resection constitutes the major curative treatment option, but a significant proportion of patients are not surgical candidates on initial evaluation. Along with the development of novel therapeutic strategies including targeted therapies and immunotherapies, a few HCCs can achieve tumor downstaging and be curatively resected.

CT-based radiomics research for discriminating the risk stratification of pheochromocytoma using different machine learning models: a multi-center study.

Objectives: The purpose of this study was to explore and verify the value of various machine learning models in preoperative risk stratification of pheochromocytoma.

Methods: A total of 155 patients diagnosed with pheochromocytoma through surgical pathology were included in this research (training cohort: n = 105; test cohort: n = 50); the risk stratification scoring system classified a PASS score of < 4 as low risk and a PASS score of ≥ 4 as high risk. From CT images captured during the non-enhanced, arterial, and portal venous phase, radiomic features were extracted.

Haeme Oxygenas-1-Induced Liver Regeneration Protects Graft Against Small-for-Size Syndrome in Rats.

Background: Haeme oxygenase (HO-1) affords protection against ischemia/reperfusion (I/R) injury; however, its effects on liver regeneration remain poorly explored. Our previous studies have shown that HO-1 is probably involved in liver regeneration, but its role in small-for-size syndrome (SFSS) is still unclear. Therefore, this study aims to investigate the effects of HO-1 on small-for-size graft (SFSG) and the underlying mechanism.

Effects of storm runoff on the spatial-temporal variation and stratified water quality in Biliuhe Reservoir, a drinking water reservoir.

Stormflow runoff is an important non-point source of pollution in drinking water reservoirs. Storm runoff is usually very turbid and contains a high concentration of organic matter, therefore affecting water quality when it enters reservoirs. In order to investigate the impact of storm runoff on spatial-temporal variation and stratification of water quality during this rainstorm event, the inflow process of the storm runoff was studied through a combination of field investigation and simulation using the Delft3D-Flow model.

Bubbles dominated the significant spatiotemporal variability and accumulation of methane concentrations in an ice-covered reservoir.

Climate-sensitive ice-covered reservoirs are critical components of methane (CH) release. However, the mechanisms that influence CH dynamics during ice-covered periods remain poorly studied. To investigate the effects of bubbles on CH dynamics, we conducted intensive field and incubation experiments in an ice-covered reservoir (ice growth, stability, and melt period) in Northeast China.

Integrating fractional amplitude of low-frequency fluctuation and functional connectivity to investigate the mechanism and prognosis of severe traumatic brain injury.

Objective: Functional magnetic resonance imaging (fMRI) has been used for evaluating residual brain function and predicting the prognosis of patients with severe traumatic brain injury (sTBI). This study aimed to integrate the fractional amplitude of low-frequency fluctuation (fALFF) and functional connectivity (FC) to investigate the mechanism and prognosis of patients with sTBI.

Methods: Sixty-five patients with sTBI were included and underwent fMRI scanning within 14 days after brain injury.

Spatiotemporal variability and environmental effects of greenhouse gases, nutrients, and dissolved carbons in an ice-covered reservoir.

Ice cover restructures the distribution of substances in ice and underlying water and poses non-negligible environmental effects. This study aimed to clarify the spatiotemporal variability and environmental effects of methane (CH), nitrous oxide (NO), total nitrogen (TN), total phosphorus (TP), dissolved organic carbon (DOC), and dissolved inorganic carbon (DIC) in ice and water columns during different ice-covered periods. We surveyed the ice-growth, ice-stability, and ice-melt periods in an ice-covered reservoir located in Northeast China.

Assessment of a Multifunctional River Using Fuzzy Comprehensive Evaluation Model in Xiaoqing River, Eastern China.

Rivers are beneficial to humans due to their multiple functions. However, human meddling substantially degrades the functions of rivers and constitutes a threat to river health. Therefore, it is vital to assess and maintain river function.

Accumulation characteristic of nitrogen in reservoirs during the ice-covered period under superimposed influence of ice and sediments: A case study of Biliuhe reservoir.

Reservoirs located in middle and high latitudes freeze for months in winter, where the accumulation characteristics of pollutants are changed by superimposed influence of salt exclusion from ice on the surface and pollution release from sediments at the bottom. Taking total nitrogen (TN) of Biliuhe reservoir in Northeast China as an example, we developed a model to simulate TN accumulation characteristics influenced by ice and sediments during the freezing period (NACISF), and quantified contributions of TN from ice and sediments. Model parameters of ice and sediments were determined by laboratory freeze-up simulation experiment and sediment release flux simulation experiment, and water quality data were obtained from field investigations.

Removal process of phosphorus during the settlement of particulates with runoff and its implication for reservoir management.

Substantial particulates and phosphorus (P) loads are carried into the reservoir by flood runoff and the P exchange between water and settling particulates under variable water conditions in the reservoir after flooding is critical to the removal of active P from water. To investigate the impact of particulate sedimentation on P changes in reservoir water, runoff samples were collected at four locations in the upstream channels of two reservoirs after a rainstorm. Two batches of particulate sedimentation simulations were conducted separately in four plexiglass columns to analyze the changes of water P and environmental factors during particulate sedimentation.

Pollution Source Apportionment and Water Quality Risk Evaluation of a Drinking Water Reservoir during Flood Seasons.

Reservoirs play an important role in the urban water supply, yet reservoirs receive an influx of large amounts of pollutants from the upper watershed during flood seasons, causing a decline in water quality and threatening the water supply. Identifying major pollution sources and assessing water quality risks are important for the environmental protection of reservoirs. In this paper, the principal component/factor analysis-multiple linear regression (PCA/FA-MLR) model and Bayesian networks (BNs) are integrated to identify water pollution sources and assess the water quality risk in different precipitation conditions, which provides an effective framework for water quality management during flood seasons.

Flood impact on the transport, transition, and accumulation of phosphorus in a reservoir: A case study of the Biliuhe Reservoir of Northeast China.

Stormflow runoff is the most important agent for phosphorus (P) input to reservoirs, as the particulates contained in runoff carry a substantial amount of P. The settling process of particulates affects the P content of water, and the distribution of particulates determines the P distribution in reservoir sediment. An understanding of flood impacts on the transport, transition, and accumulation of P in a reservoir is critical to reservoir management.

Response of a Coastal Groundwater System to Natural and Anthropogenic Factors: Case Study on East Coast of Laizhou Bay, China.

With a shifting climate pattern and enhancement of human activities, coastal areas are exposed to threats of groundwater environmental issues. This work takes the eastern coast of Laizhou Bay as a research area to study the response of a coastal groundwater system to natural and human impacts with a combination of statistical, hydrogeochemical, and fuzzy classification methods. First, the groundwater level dynamics from 1980 to 2017 were analyzed.

Water quality assessment and pollution source apportionment in a highly regulated river of Northeast China.

Dams and sluices break down the river continuum, alter the river hydrological regime, and intercept the migration processes of nutrients and pollutants. The regulation of dams and sluices will have great impacts on water quality characteristics in the river basin. In this study, variable fuzzy pattern recognition model (VFPR), principal component analysis/factor analysis (PCA/FA), and the absolute principal component score-multiple linear regression (APCS-MLR) were used to assess the water quality and identify the potential pollution sources in a highly regulated river of Northeast China.

Impact of long-term water level fluctuation on the distribution, transport, and fate of phosphorus in reservoir sediment.

Water level fluctuation zone (WLFZ) with changeable environmental conditions would affect the transport and release of nutrients in the sediment. To investigate the influence of long-term water level fluctuations on sediment phosphorus (P), a reservoir sediment partitioning method based on historical water level was developed and applied in the Biliuhe Reservoir. The reservoir sediment was divided into frequent fluctuation zone (FFZ), fluctuation zone of continuous droughts (DFZ), and continuously submerged zone (CSZ).

Evaporation and concentration of desulfurization wastewater with waste heat from coal-fired power plants.

The reduction of wet desulfurization wastewater is one of the important tasks of coal-fired power plants, and it is important for achieving "zero emissions." Evaporation and concentration (E&C) with waste heat is an effective way to reduce wastewater. Here, two typical types of industrial desulfurization wastewater are used to study the change rule of pH and total dissolved solids during wastewater concentration in a circulating evaporation tower.

Metal distribution in sediments of a drinking water reservoir: influence of reservoir morphometry and hydrodynamics.

Metal(loid)s in the reservoir sediment tend to be released into the water column when encountering disturbances and thus pose threats to the aquatic system. In this study, sediment and pore water samples collected from eight cross sections in the Biliu River Reservoir (Dalian, China) were analyzed to determine the spatial distributions of six metal(loid)s and their associations with reservoir morphometry and hydrodynamics. The results show that total metal concentrations of the sediments are higher at the sites with greater water depths and are influenced by the reservoir morphometry.

Neuroendocrine carcinoma in the extrahepatic biliary tract: A case report and literature review.

Rationale: Neuroendocrine carcinoma (NEC) arising from the extrahepatic biliary tracts (EHBTs) is rare, and thus its management and prognosis remain poorly clarified. We herein describe a case of NEC in the perihilar EHBTs, and review the literature, together with a comparison between NECs in the perihilar and distal EHBTs, to elucidate the management strategy and oncological outcome of this rare entity.

Patient Concerns: A 62-year-old Chinese male was admitted with complaints of painless jaundice.

Hepatic rupture: A case report of a severe complication of percutaneous catheter drainage.

Rationale: Currently, percutaneous catheter drainage (PCD) is regarded as the first-line treatment modality of pyogenic liver abscess. Severe complications associated with PCD were uncommon. Hepatic rupture is an uncommon but life-threatening liver trauma with high mortality.

The Role of AChE in Swimming Behavior of : Correlation Analysis of Both Parameters Affected by Deltamethrin and Methomyl Exposure.

The unpredictable toxicity of insecticides may cause behavior disorder of biological organisms. In order to assess the role of acetylcholinesterase (AChE) in swimming behavior of , a correlation analysis of both parameters in 24 h exposure of deltamethrin (DM) and methomyl (MT) was investigated. The behavior responses of in DM (13.