Publications by authors named "Shi-yong Lian"
In 2005, a program named "Early Detection and Early Treatment of Esophageal and Cardiac Cancer" (EDETEC) was initiated in China. A total of 8279 residents aged 40-69 years old were recruited into the EDETEC program in Linzhou of Henan Province between 2005 and 2008. Howerer, the cost-benefit of the EDETEC program is not very clear yet.
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- A genome-wide association study was conducted on esophageal squamous cell carcinoma (ESCC) involving 1,077 ESCC patients and 1,733 control subjects, focusing on the Chinese Han population.
- The study successfully replicated findings in larger cohorts, identifying two new genetic risk factors for ESCC: PLCE1 and C20orf54, with strong statistical significance.
- PLCE1 is linked to essential cellular functions like growth and apoptosis, while C20orf54 is involved in riboflavin transport, highlighting their potential roles in ESCC and gastric cardia adenocarcinoma (GCA) risk.
[Period survival analysis of esophageal cancer in Linzhou city of Henan province].
Zhonghua Yu Fang Yi Xue Za Zhi
December 2009
Objective: To analyze the survival level and variation of esophageal cancer in Linzhou city of Henan province from 1988 to 2004, and evaluate the effects of diagnosis and treatments on esophageal cancer in this area.
Methods: All incidence and death records for esophageal cancer during 1988 to 2004 were collected from Linzhou Tumor Registry. Cases with duplicate information or death certificate only were excluded.
[The trends on the mortality for esophagus and stomach cancers in Linzhou city from 1988 to 2003].
Zhonghua Yu Fang Yi Xue Za Zhi
June 2007
Objective: Using the data on death for esophagus and stomach cancers in Linzhou cancer registration system, the mortality was described as well as the changing trend was analyzed.
Methods: 18 240 death recorders for the both cancers during 1988 to 2003 were drawn from Linzhou cancer registration system. Of which, 10138 cases were esophageal cancer and 8102 cases were gastric cancer.