Thiostrepton confers protection against reactive oxygen species-related apoptosis by restraining FOXM1-triggerred development of gastric cancer.

Gastric cancer is a leading cause of tumor-associated death worldwide. Metastasis and chemoresistance are crucial barriers for gastric cancer treatment. The Forkhead Box M1 (FOXM1) transcription factor has been reported as a promising treatment target for various types of tumors, but its effects on gastric cancer progression are not fully understood.

[Stored autologous blood transfusion does not increase recurrence of prostate cancer after radical prostatectomy: A preliminary study].

Objective: To analyze the association of stored autologous blood transfusion (SABT) with tumor recurrence in PCa patients after radical prostatectomy and explore the application of SABT in this surgical procedure.

Methods: Forty-five PCa patients underwent radical prostatectomy in our hospital in recent five years, of whom, 20 received SABT (group A) and the other 25 allogeneic blood transfusion (group B) intraoperatively. After surgery, we followed up the patients regularly for 3－66 months by examination of the levels of total PSA (tPSA) and free PSA (fPSA), digital rectal examination (DRE), and MRI to observe the biochemical recurrence of the tumor.

[Early diagnosis of prostate cancer by combined use of Trp-p8 expression and PSA density of the transition zone].

Objective: To study the expression of the Trp-p8 protein in the prostate tissue of the PSA "grey zone" with different PSA density of the transition zone (PSADTZ) and explore the value of determining Trp-p8 expression and PSADTZ in the early diagnosis of prostate cancer (PCa).

Methods: This study involved 30 cases of benign prostatic hyperplasia (BPH) and another 30 cases of PCa with different PSADTZ values. Using a data imaging and analysis system, we determined the expression levels of Trp-p8 in BPH and PCa tissues and analyzed their correlation with PSADTZ.

[Management of moderate to severe pediatric concealed penis in children by Devine's technique via incision between the penis and scrotum].

Objective: To search for a simple and effective surgical approach to the management of moderate to severe pediatric concealed penis in children.

Methods: We used Devine's technique via incision between the penis and scrotum in the treatment of 68 cases of moderate to severe pediatric concealed penis. The patients were aged 3 -13 (mean 6.

Trinitratobis{N'-[1-(2-pyridyl)ethylidene]isonicotinohydrazide}cerium(III): a three-dimensional cerium-organic supramolecular structure.

The Ce(III) ion in the title complex, [Ce(NO(3))(3)(C(13)H(12)N(4)O)(2)], is 12-coordinated by six chelating nitrate O atoms and six donors (2 O and 4 N atoms) of two N'-[1-(2-pyridyl)ethylidene]isonicotinohydrazide ligands, exhibiting a bicapped pentagonal-antiprism-type coordination geometry. The title complex possesses C(2) point symmetry and is located on a twofold crystallographic axis. Each molecule is linked with four surrounding molecules by four N-H.

Bis[2-hydroxy-N'-(3-phenylprop-2-enylidene)benzohydrazidato-kappa2N',O]bis(methanol-kappaO)nickel(II) and bis[2-hydroxy-N'-(3-phenylprop-2-enylidene)benzohydrazidato-kappa2N',O]bis(pyridine-kappaN)nickel(II).

In the two title complexes of cinnamaldehyde salicyloylhydrazone [or 2-hydroxy-N'-(3-phenylprop-2-enylidene)benzohydrazide], [Ni(C(16)H(13)N(2)O(2))(2)(CH(4)O)(2)], (I), and [Ni(C(16)H(13)N(2)O(2))(2)(C(5)H(5)N)(2)], (II), the Ni(II) atoms lie on crystallographic inversion centres and have distorted octahedral geometries. The equatorial plane is defined by two carbonyl O atoms and two hydrazine N atoms of two bidentate trans-oriented salicyloylhydrazone ligands. The axial positions are occupied by two O atoms from two coordinated methanol molecules in (I) and by two N atoms from two coordinated pyridine molecules in (II).

(Acetyl-acetonato-κO,O')-aqua-[salicyl-aldehyde nicotinoylhydrazonato(2-)-κO,N,O']manganese(III).

The Mn(III) atom in the title complex, [Mn(C(13)H(9)N(3)O(2))(C(5)H(7)O(2))(H(2)O)], is coordinated by three donors from a dianionic ligand, salicylaldehyde nicotylhydrazone, two O atoms from an acetyl-acetonate anion and a water mol-ecule in a distorted octa-hedral geometry. There is an extended two-dimensional supra-molecular motif resulting from O-H⋯N hydrogen bonds between the coordinated water mol-ecule and a hydrazine N or pyridine N atom, and from C-H⋯O hydrogen bonds between a CH group and the phenolate O atom.

[Prevention of incontinence after radical prostatectomy].

Objective: To discuss the effect of urine control after radical retropubic prostatectomy by preserve the membranous part of sphincter urethrae and the neurovascular bundle, or to rebuild the bladder neck.

Methods: The radical retropubic prostatectomy was performed on a total of 32 cases of prostate cancer. We preserve the membranous part of sphincter urethrae and the neurovascular bundle lateral to the prostate.

Synthesis, structure, and magnetism of a ferric 24-azametallacrown-8 complex.

A new pentadentate N-isobutyrylsalicylhydrazidate ligand (H(3)ibushz, C(11)H(14)N(2)O(3)) and a self-assembly synthesis of the first 24-azametallacrown-8, [Fe(8)(C(11)H(11)N(2)O(3))(8)(CH(3)OH)(8)].0.5CH(2)Cl(2).

[Studies on infrared and UV-vis spectra of azametallacrown complexes containing Mn(III), Fe(III) or Co(III)].

IR and UV-vis spectral properties of azametallacrown complexes containing Mn(III), Fe(III) or Co(III) were investigated. The relation between the main IR bands in 400-4,000 cm-1 and the structure of azametallacrown complexes were discussed. The absorption bands of nu(C=O), nu(NH), delta(NH) + nu(CN) and delta(NH) which existed in the IR spectra of the ligands disappeared in the IR spectra of the complexes.