Comparison of visual effects of FS-LASIK for myopia centered on the coaxially sighted corneal light reflex or the line of sight.

Aim: To compare visual quality after femtosecond laser keratomileusis (FS-LASIK), between the coaxially sighted corneal light reflex (CSCLR) group and conventional ablation line of sight (LOS) group.

Methods: In total, 243 eyes (122 patients) were treated with centration on the CSCLR (visual axis) and 238 eyes (119 patients) treated with centration on the pupil center (LOS). Postoperative outcomes [uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA)], safety index, efficacy index, refractive outcome, ablation center distance from the visual axis, corneal high-order aberrations, subjective discomfort glare and shadowing incidence rate, and contrast sensitivity at 1, 3, and 6mo were measured and compared.

[Comparison of cornea flap made by femtosecond laser and microkeratome in laser in situ keratomileusis].

Objective: To determine flap thickness variation in 110 µm thickness flap made by FS200 femtosecond laser and sub-Bowman keratomileusis (SBK) microkeratome for studying the potential factors that affect the flap thickness.

Methods: It was a case-control study. Sixty patients were divided into two groups for laser in situ keratomileusis.

Effects of intensive control of blood glucose and blood pressure on microvascular complications in patients with type II diabetes mellitus.

Aim: To evaluate the effects of intensive control of blood glucose and blood pressure on microvascular complications in patients with type II diabetes by comparing the therapeutic effects of intensive and standard treatment in patients with type II diabetes.

Methods: A total of 107 patients with type II diabetes were randomly assigned into intensive and standard treatment groups. Patients in the intensive treatment group received preterax (perindopril/ indapamide) to control blood pressure, and gliclazide (diamicron) MR to control blood glucose.

[Three kinds of phakic intraocular lens for correction of high myopia].

Objective: To evaluate the efficacy, safety and stability of three kinds of phakic intraocular lens implantation for the correction of high myopia.

Methods: This study included 208 eyes of 110 patients with a mean age of 31 years (21 - 53) from December 2003 to December 2009. Angle-supported lens (Phakic 6H, OII) were inserted into 113 eyes, iris-fixated lens (Artisan, OPHTEC) were inserted into 53 eyes and implantable contact lens (ICL) (V4, STAAR) were inserted into 41eyes.

Ocular manifestations of Alport syndrome.

Aim: To analyze the clinical manifestation of Alport syndrome, especially the ocular features.

Methods: The physical, ophthalmologic and audiologic examination results of thirty-two patients with Alport syndrome were analyzed retrospectively.

Results: Thirty (93.

[Expression and significance of GST-Pi and HIF-1alpha in bladder carcinoma].

Background & Objective: Multidrug resistance plays an important role in chemotherapy failure of bladder cancer, but its mechanism is unclear. Hypoxia in tumors is generally associated with chemoresistance. However, the correlation of nuclear transcription factor hypoxia-inducible factor-1 (HIF-1) to multidrug resistance transporter glutathione-S-transferase-Pi (GST-Pi) has not been investigated.

[Intravesial instillation of recombination interferon-alpha and pirarubicin in the prophylaxis of local recurrence after resection of the superficial bladder cancer].

Background & Objective: Superficial transitional cell carcinoma (TCC) of urinary bladder tends to recur after transurethral surgery. This study was designed to evaluate the effect of interferon-alpha (IFN-alpha)and pirarubicin (THP) on decreasing postoperative recurrence of superficial bladder cancer.

Methods: Recombinant IFN-alpha and THP has been used in clinical study.

[An experimental study of the inhibition of tamoxifen on rat model of benign prostatic hyperplasia].

Objectives: To study the inhibitory mechanism of tamoxifen on benign prostatic hyperplasia.

Methods: The Wistar male adult rats were injected into muscle with testosterone propionate 4-6 mg/kg, simultaneously were irrigated into stomach with tamoxifen citrate 0.21 mg/kg.