Publications by authors named "Shi-qun Liu"
Objective: To understand the association between plasminogen activator inhibitor-1 (PAI-1) gene 4G/5G polymorphism and type 2 diabetic nephropathy (DN) in Chinese Han patients in Guangdong Province.
Methods: PAI-1 gene 4G/5G polymorphism was analyzed in 26 normal individuals, 77 patients with type 2 diabetic nephropathy and 70 type 2 diabetic patients without nephropathy (DNN) by polymerase chain reaction-restriction fragment length polymorphism.
Results: The 4G/4G genotype frequencies of PAI-1 gene were higher in DN than in DNN patients (0.
[Association of angiotensinogen gene polymorphism with hypertension in type 2 diabetic patients].
Di Yi Jun Yi Da Xue Xue Bao
November 2003
Objective: To investigate the relationship between angiotensinogen (AGT) gene polymorphism and hypertension in type 2 diabetic patients.
Methods: A total of 240 patients with type 2 diabetes mellitus were divided into normotensive and hypertensive groups according to their blood pressure measurement, and their fasting plasma glucose, total cholesterol, triglyceride, high-density lipoprotein, low-density lipoprotein and very-low-density lipoprotein were measured. The AGT genotypes were detected by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).
[Serum uric acid in type 2 diabetic patients complicated by stroke].
Di Yi Jun Yi Da Xue Xue Bao
January 2002
Objective: To investigate the association of hyperuricemia with the incidence of stroke in type 2 diabetic patients.
Methods: Sixty type 2 diabetic patients with stroke, 75 patients with simple stoke and 67 simple type 2 diabetic patients were randomly selected from the hospitalized patients. The serum levels of uric acid (UA), total cholesterol (TC), triglyceride (TG), low-density lipoprotein-cholesterol(LDL), very-low-density lipoproteincholesterol (VLDL) and high-density lipoprotein- cholesterol (HDL) of all the patients were determined and comparison between the groups performed.