Background: Abdominal wall endometriosis can occur secondary to gynecological and obstetric pelvic laparotomy; however, this is a rare clinical event. There are few cases of endometriosis involving the incision site of a laparoscopic surgery, especially for those of the endometrial nodule at the umbilical trocar port site where the camera is placed.
Case Summary: We describe the case of a 37-year-old woman who presented with a 2-year history of a tough swelling below the umbilicus, which presented periodical pain during menstruation.
Sichuan Da Xue Xue Bao Yi Xue Ban
November 2018
Objective: To investigate whether the methylene tetrahydrofolate reductase () 677C/T polymorphisms were related to the prevalence of 46,XX premature ovarian failure (POF) in Chinese Han women.
Methods: Infertile Chinese Han women were divided into 2 groups: POF group (=147) and control group (=166).The expression of gene in peripheral blood was determined by RT-PCR.
Sichuan Da Xue Xue Bao Yi Xue Ban
July 2013
Objective: To investigate the preventing effect of Fukang oral liquid (fuk) in intrauterine adhesions and its effects on the expression of TGFbeta-1, PAI-1 and MMP-9 in endometrium of rats with intrauterine adhesions.
Methods: 50 female wistar rats were divided into high, medium, low dose of Fukang oral liquid group (Hfuk, Mfuk, Lfuk), blank control group (Bcon), and model control group (Mcon) (n = 10 in each group). The rats in Hfuk, Mfuk and Lfuk groups were treated with intragastric administration of 4 mL, 2 mL and 1 mL Fukang Oral Liquid per day, while the rats in Mcon group and Bcon group received 2 mL physiological saline intragastric administration per day.
Cytochrome P450 1B1 (CYP1B1) is a key P450 enzyme, which could catalyze the formation of 4-hydroxy estrogen metabolites and play a role in estrogen-dependent cancers. We hypothesized that genetic variant in CYP1B1 may modify individual susceptibility to cervical cancer. The aim of this study was to evaluate the association between CYP1B1 C4326G polymorphism and cervical cancer risk in Chinese women.
View Article and Find Full Text PDFBackground: Previous studies investigating the association between X-ray repair cross-complementation group 1(XRCC1) polymorphisms and cervical cancer (CC) risk has provided inconsistent results. The aim of our study was to assess the association between the XRCC1 gene Arg399Gln, Arg194Trp, Arg280His polymorphisms and risk of CC.
Methods: Two investigators independently searched the Medline, Embase, CNKI, and Chinese Biomedicine Databases for studies published before March 2011.
Estrogen receptor-alpha (ER-α) polymorphisms have been hypothesized to be associated with the risk of endometriosis (EMT) development by many epidemiological studies, however, the available results were conflicting. To derive a more precise estimation of association between the ER-α PvuII (T/C) and XbaI (A/G) polymorphisms and risk of EMT, we performed a meta-analysis. Summary odds ratios (ORs) and 95% confidence intervals (95% CIs) for ER-α polymorphisms and EMT were calculated in a fixed-effects model and a random-effects model when appropriate.
View Article and Find Full Text PDFSichuan Da Xue Xue Bao Yi Xue Ban
March 2010
Objective: To compare the morphology and proliferation of primordial and primary follicles in fresh and vitrificated human ovarian tissues.
Methods: Human ovarian tissues were cryopreserved by direct cover vitrification (DCV) for 2 weeks. The morphology of the primordial and primary follicles from the frozen-thawed tissues was compared with those from the fresh tissues.
Sichuan Da Xue Xue Bao Yi Xue Ban
May 2008
Objective: To determine the level of NO in the peritoneal fluids in patients with endometriosis and to evaluate the impact of NO on human sperm motility.
Methods: Peritoneal fluids were taken from 19 patients with Endometriosis, 16 infertile patients with Endometriosis, and 21 patients without Endometriosis (control group). The macrophages in the peritoneal fluids were segregated and cultivated.
Sichuan Da Xue Xue Bao Yi Xue Ban
May 2008
Objective: To evaluate the impact of progesterone in the peritoneal fluid on human sperm motility in the infertile patients with endometriosis.
Methods: Peritoneal fluids were collected from 41 patients by laparoscopy, of which 17 were infertile patients with endometriosis, 11 were fertile patients with endometriosis and 13 were fertile controls. The concentrations of progesterone in the peritoneal fluids were measured by the immulyze-enzyme amplified luminescence system.
Sichuan Da Xue Xue Bao Yi Xue Ban
March 2007
Objective: To evaluate the effect of rosiglitazone (ROS) on integrin beta1 expression and apoptosis of proximal tubular cell exposed to high glucose.
Methods: The proximal tubular cells of rats were cultured in vitro and divided into 6 groups: control group, normal glucose (5 mmol/L) group, high glucose (30 mmol/L) group, only ROS (10 micromol/L) group, glucose (30 mmol/L)+ROS (5 micromol/L) group, and glucose (30 mmol/L) +ROS (10 micromol/L) group. The cells were cultured for 48 hrs and the integrin beta1 expressions were detected by Western blot and RT-PCR; The apoptosis was evaluated by flow cytometry after the cells were cultured for 24, 48, 72 hrs.