Publications by authors named "Shi-jun Wei"
Background: Arthritis is a prevalent and debilitating condition that affects a significant proportion of middle-aged and older adults worldwide. Characterized by chronic pain, inflammation, and joint dysfunction, arthritis can severely impact physical function, quality of life, and mental health. The overall burden of arthritis is further compounded in this population due to its frequent association with depression.
View Article and Find Full Text PDFSuppressor of Mek1 (Smek1) is a regulatory subunit of protein phosphatase 4. Genome-wide association studies have shown the protective effect of SMEK1 in Alzheimer's disease (AD). However, the physiological and pathological roles of Smek1 in AD and other tauopathies are largely unclear.
View Article and Find Full Text PDFBackground: To investigate the prevalence of and risk factors for leukopenia in tuberculosis patients and the impact of anti-tuberculosis regimens on the occurrence of leukopenia in newly treated tuberculosis patients.
Methods: A total of 1,904 tuberculosis patients were included in the study. A cross-sectional survey of the prevalence of leukopenia was initially conducted, and then factors influencing leukopenia were identified using Logistic regression analysis.
Article Synopsis
- The study compares primary wound closure (PWC) and delayed wound closure (DWC) in treating severe open tibial fractures with internal fixation and vacuum-assisted wound coverage.
- Results showed no significant differences in complications like deep infection or amputation between PWC, DWC, and external fixation groups, although PWC had lower rates of these issues.
- The findings suggest that PWC might be as effective or better than DWC for managing Gustilo-Andersen type IIIA and IIIB open tibial fractures.
Objective: The purpose of this study is to evaluate a surgical strategy for pilon fractures based on ankle position/initial direction of fracture displacement at the time of injury.
Methods: Sixty-nine patients were categorized into groups based on ankle position at the time of the injury: Group I (varus), Group II (valgus), Group III (dorsiflexion), Group IV (plantarflexion), and Group V (neutral). The American Orthopedic Foot and Ankle Society (AOFAS) score was determined at 12 months.
Objective: To explore the choice and effect of internal fixation in treating upper cervical vertebrae instability through anterior approach.
Methods: From March 2000 to September 2010,83 patients with upper cervical vertebrae instability were treated with internal fixation through anterior approach. There were 59 males and 24 females with a mean age of 42 years old (ranged, 20 to 68).