Temporal dynamics of immune cell patterns in bladder cancer patients receiving Bacillus Calmette-Guérin therapy.

Background: Bacillus Calmette-Guérin (BCG) is capable of enhancing the infiltration of immune cells into the tumour. However the temporal dynamics of immune cell patterns in patients receiving BCG instillation remains unclear.

Methods: Ninety-six patients who underwent intravesical BCG therapy, comprising 46 responders and 50 non-responders, were retrospectively enroled to explore the evolving immune landscape.

LAFEM: A Scoring Model to Evaluate Functional Landscape of Lysine Acetylome.

Protein lysine acetylation is a critical post-translational modification involved in a wide range of biological processes. To date, about 20,000 acetylation sites of Homo sapiens were identified through mass spectrometry-based proteomic technology, but more than 95% of them have unclear functional annotations because of the lack of existing prioritization strategy to assess the functional importance of the acetylation sites on large scale. Hence, we established a lysine acetylation functional evaluating model (LAFEM) by considering eight critical features surrounding lysine acetylation site to high-throughput estimate the functional importance of given acetylation sites.

[Analysis of possible factors that impact parents to accept dental general anesthesia].

Purpose: To analyze the possible factors that impact parents to accept dental general anesthesia (DGA) in pediatric dentistry, thus provide some reference when a pediatric dentist suggests DGA technique to parents in clinical practice.

Methods: DGA technique was explained to 299 surveyed subjects (mother or father), and then the questionnaires were filled in. Parental acceptance rate was determined by a 100mm visual analogue scale (VAS).

[Results of 30 children treated under dental general anesthesia in pediatric dentistry].

Purpose: To determine the age and sex characteristics of the children and type of dental procedures performed under dental general anesthesia (DGA) and to assess the results after six months to one year's follow-up.

Methods: A sample of 30 patients treated under dental general anesthesia (DGA) during 2006-2007 in the Department of Pediatric Dentistry of China Medical University was reviewed. All the teeth were treated one time.

[Survey of parental acceptance rate to behavior management techniques used in pediatric dentistry].

Purpose: To investigate the parental acceptance rate to behavior management techniques (BMT) used in pediatric dentistry.

Methods: Two hundred and eighty-five subjects (mother or father) were included in this survey. Five behavior management techniques including (1)tell-show-do; (2)voice control; (3)passive restraint; (4)sedation; (5) general anesthesia commonly used in pediatric dentistry were explained to the parents and then filled the questionnaires by either of the parents, including the parental age, gender, educational level and income, The answerer rated their acceptance of each technique using a visual analogue scale (VAS), a continuous scale ranging from 0 to 100mm.