The protective effect and mechanism of glycosides of on rats in middle cerebral artery occlusion (MCAO) model.

Cerebral ischemia-reperfusion injury (CIRI) occurs frequently clinically as a complication following cardiovascular resuscitation resulting in neuronal damage specifically to the hippocampal CA1 region with consequent cognitive impairment. Apoptosis and oxidative stress were proposed as major risk factors associated with CIRI development. Previously, glycosides obtained from (CGs) were shown to play a key role in counteracting CIRI; however, the underlying mechanisms remain to be determined.

A Case of Floating-Harbor Syndrome with "Growth and Language Development Delay" as Its Clinical Manifestation.

Background: Floating-Harbor syndrome (FHS) is a rare autosomal dominant inherited disease characterized primarily by short stature, delayed language development, and typical facial features. There are currently few case reports, diagnoses and treatments for these syndromes at home and abroad.

Case Description: This study reports a case of a boy with "growth and language development delay" as the predominant clinical manifestation.

Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.

Introduction: The etiology of Parkinson's disease (PD) is still unknown. Until now, oxidative stress and neuroinflammation play a crucial role in the pathogenesis of PD. However, the specific synergistic role of oxidative stress and neuroinflammation in the occurrence and development of PD remains unclear.

Serum Fat-Soluble Vitamin Levels of 6,082 Minors in Zhuzhou City.

Objective: To explore the nutritional status of serum fat-soluble vitamins such as vitamin A, 25-hydroxyvitamin D, and vitamin E of minors in the Zhuzhou area to provide a scientific basis for clinical guidance to supplement fat-soluble vitamins reasonably.

Method: A total of 6,082 minors who underwent physical examination from January 2017 to February 2019 in the Children's Health Department of Zhuzhou Hospital affiliated with XiangYa School of Medicine of Central South University were selected as the subjects to measure the levels of serum fat-soluble vitamins A, D, and E.

Results: (1) Their average levels of serum vitamin A, 25-hydroxyvitamin D, and vitamin E were (0.

Effects of intraperitoneal injection of lipopolysaccharide-induced peripheral inflammation on dopamine neuron damage in rat midbrain.

Introduction: Current studies have documented neuroinflammation is implicated in Parkinson's disease. Recently, growing evidence indicated peripheral inflammation plays an important role in regulation of neuroinflammation and thus conferring protection against dopamine (DA) neuronal damage. However, the underlying mechanisms are not clearly illuminated.

α4β7 CD4 T cells are prone to be infected by HIV-1 and associated with HIV-1 disease progression.

Introduction: To investigate the characteristics of β7 CD4 T cells during HIV-1 infection and the relationship between β7 CD4 T cells and HIV-1 disease progress.

Methods: This study enrolled 124 HIV-1-infected patients, including 80 treatment naïve patients (TNs), 41 patients who underwent antiretroviral therapy (ARTs), and three long-term no progression patients (LTNPs). Nineteen matched healthy subjects were included as controls (HCs).

A Quantum secure sharing protocol for Cloud data based on proxy re-encryption.

A quantum scheme for cloud data sharing based on proxy re-encryption is proposed. The user Alice stores the cipher-text of her data on cloud data center. When Alice wants to share her data with another user Bob, Alice is called the delegator and Bob is called the delegatee.

[Effects of simulated nitrogen and sulfur deposition on litter decomposition rate in an evergreen broad-leaved forest in the Rainy Area of Western China.].

To examine the effects of nitrogen and sulfur deposition on litter decomposition rate, a one-year field experiment was conducted with the litter bag method from April 2013 to April 2014 in an evergreen broad-leaved forest in the Rainy Area of Western China. There were nine treatments with three nitrogen levels and three sulfur levels, including control (CK), low nitrogen deposition (LN, 50 kg N·hm·a), high nitrogen deposition (HN, 150 kg N·hm·a), low sulfur deposition (LS, 200 kg S·hm·a), high sulfur deposition (HS, 400 kg S·hm·a), low nitrogen and low sulfur deposition (LNLS), high nitrogen and low sulfur deposition (HSLS), low nitrogen and high sulfur deposition (LNHS), and high nitrogen and high sulfur deposition (HNHS). The results showed that the leaf litter residual rate ranged from 57.

Normal Electrocardiogram of Bama Miniature Pigs (Sus scrofa domestica).

This study determined the normal ECG patterns and values for Bama miniature pigs. Standard limb-lead ECG were recorded from 120 clinically healthy, unanesthetized piglets (age, 2 to 4 mo). The values for the ECG parameters (mean ± 1 SD) were: heart rate, 125.

[Efficacy of combination antiviral therapy following childbirth in pregnant HBV carriers receiving telbivudine for prevention of mother-to-child transmission].

Objective: To observe the clinical efficacy of combination therapy with peg-IFNalpha and adefovir (CPIA) in women who were hepatfis B virus (HBV) carriers and had just given birth and received telbivudine (LdT) during pregnancy for prevention of mother-to-child transmission.

Methods: One-hundred-and-fifty third trimester-pregnant women who were HBV carriers with highly-viremic were treated with LdT until time of birth. After delivery, those women with alanine aminotransferase (ALT) level exceeding two times the upper limit of normal and HBV DNA level that had decreased more than 31 gIU/mL or hepatitis B e antigen (HBeAg) titer that had decreased more than 50% were switched to CPIA for 96 weeks.

Clinical features of adverse reactions associated with telbivudine.

Aim: To analyze the clinical features and risk factors of adverse reactions associated with telbivudine.

Methods: Clinical data were collected from cases that presented with serious adverse reactions to telbivudine. We analyzed general information and medicine status, clinical features, results of examination, and misdiagnosis.

[Observation on therapeutic effect of chronic prostatitis treated mainly by warming needle moxibustion].

Objective: To explore an effective method for increasing therapeutic effect on chronic prostatitis.

Methods: Eighty-two cases of chronic prostatitis were randomly divided into two groups. The western medicine group of 42 cases were treated with routine western medicine combined with retention enteroclysis of 30 g Danshen (Red Sage Root) decoction; the warming needle moxibustion plus western medicine group of 40 cases were treated with the western medicine of the western medicine group plus warming needle moxibustion at Guanyuan (CV 4), Qihai (CV 6) and Zhongji (CV 3), etc.