Lung Cancer Risk Attributable to Active Smoking in China: A Systematic Review and Meta-Analysis.

Objective: No consensus exists on the relative risk ( ) of lung cancer (LC) attributable to active smoking in China. This study aimed to evaluate the unified of LC attributable to active smoking among the Chinese population.

Methods: A systematic literature search of seven databases was conducted to identify studies reporting active smoking among smokers nonsmokers in China.

Impact of Smoke-Free Legislation on Acute Myocardial Infarction and Subtypes of Stroke Incidence in Shenzhen, China, 2012-2016: An Interrupted Time Series Analysis.

Objective: This study assesses the impact of smoke-free legislation on the incidence rate for acute myocardial infarction (AMI) and stroke in Shenzhen.

Methods: Data on ischemic ( = 72,945) and hemorrhagic ( = 18,659) stroke and AMI ( = 17,431) incidence covering about 12 million people in Shenzhen from 2012 to 2016 were used. Immediate and gradual changes in incidence rates were analyzed using segmented Poisson regression.

A digital workflow to predict facial aesthetics in patients with maxillofacial trauma with implant retained prostheses.

Purpose To introduce a digital workflow for the prediction of facial aesthetics, especially in patients with dentation deformity caused by maxillofacial trauma.Methods Cone-beam computed tomography (CBCT) and three-dimensional facial scans of patients with radiographic prostheses were collected. The aforementioned data were uploaded to ProPlan CMF software and merged to generate a virtual patient with craniofacial hard tissue, realistic facial soft tissue, and remaining dentition.

The Association between Exposure to Second-Hand Smoke and Disease in the Chinese Population: A Systematic Review and Meta-Analysis.

Objective: To analyze the association between exposure to second-hand smoke (SHS) and 23 diseases, categorized into four classifications, among the Chinese population.

Methods: We searched the literature up to June 30, 2021, and eligible studies were identified according to the PECOS format: Participants and Competitors (Chinese population), Exposure (SHS), Outcomes (Disease or Death), and Study design (Case-control or Cohort).

Results: In total, 53 studies were selected.

[Professor -'s experience in the clinical application of "Dayingxiang"].

The paper introduces professor -'s experience in treatment with acupuncture-moxibustion at "Dayingxiang". Based on the application of Neiyingxiang (internal LI 20), professor defines the entire nasal cavity and its adjacent nasopharynx as "Dayingxiang", of which, "Neiyingxiang" and "Biyandian" (nasopharynx point) are commonly stimulated with acupuncture-moxibustion. "Dayingxiang" may regulate lung and promote the circulation of the marrow sea in treatment of the disorders of lung system and the marrow.

Relationships Between Diurnal Changes of Tongue Coating Microbiota and Intestinal Microbiota.

The oral cavity and the intestine are the main distribution locations of human digestive bacteria. Exploring the relationships between the tongue coating and gut microbiota, the influence of the diurnal variations of the tongue coating microbiota on the intestinal microbiota can provide a reference for the development of the disease diagnosis and monitoring, as well as the medication time. In this work, a total of 39 healthy college students were recruited.

A Study of Logistic Regression for Fatigue Classification Based on Data of Tongue and Pulse.

Methods: The Tongue and Face Diagnosis Analysis-1 instrument and Pulse Diagnosis Analysis-1 instrument were used to collect the tongue image and sphygmogram of the subhealth fatigue population ( = 252) and disease fatigue population ( = 1160), and we mainly analyzed the tongue and pulse characteristics and constructed the classification model by using the logistic regression method.

Results: The results showed that subhealth fatigue people and disease fatigue people had different characteristics of tongue and pulse, and the logistic regression model based on tongue and pulse data had a good classification effect. The accuracies of models of healthy controls and subhealth fatigue, subhealth fatigue and disease fatigue, and healthy controls and disease fatigue were 68.

Vaccination coverage determinants in low uptake areas of China: a qualitative study of provider perspectives in Sichuan, Guangdong, and Henan Provinces.

China's immunization programme is relatively strong, with latest WHO-UNICEF monitoring rates for 2019 showing national vaccination coverage over 90%. However, vaccination coverage is heterogeneous, varying across geographic regions, rural-urban communities, and sub-populations. We conducted a qualitative study from a critical realist perspective, analyzing semi-structured interviews with 26 vaccination providers in three provinces, selected to represent regional socioeconomic disparities across Eastern, Central, and Western China.

The effects and mechanism of paeoniflorin in promoting osteogenic differentiation of MC3T3-E1.

Background: The incidence of osteoporosis and osteoporotic fractures is increasing every year. Traditional Chinese Medicine (TCM) can shed new light on the treatment of osteoporosis. This study aimed to explore the role and mechanism of paeoniflorin in promoting osteogenic differentiation of an osteoblast precursor cell line (MC3T3-E1).

[Professor -'s clinical experience in staging treatment for post-stroke dysphagia].

The paper summarizes professor -'s clinical experience in staging treatment for post-stroke dysphagia. Professor - adheres to "essence and marrow deficiency and primary decline" as the pathogenesis and "conducting from " as the treating principle. By regulating the conception vessel and the governor vessel and focusing on meridians, in association with meridian differentiation and the location differentiation, professor provides the staging treatment for post-stroke dysphagia.

['s experience for treating press ulcer with fire-moxibustion].

To summarize 's experience for treating press ulcer with fire-moxibustion. Through syndrome differentiation and examined factors, believes that the disease is caused by deficiency and blood stasis, and advocates that the treatment should be weighed against deficiency and excess, and selection by stages. The cotton-moxibustion is used to diffusing and obstruction-removing and blood duingⅠstage of press ulcer.

A New Method for Syndrome Classification of Non-Small-Cell Lung Cancer Based on Data of Tongue and Pulse with Machine Learning.

Objective: To explore the data characteristics of tongue and pulse of non-small-cell lung cancer with Qi deficiency syndrome and Yin deficiency syndrome, establish syndrome classification model based on data of tongue and pulse by using machine learning methods, and evaluate the feasibility of syndrome classification based on data of tongue and pulse.

Methods: We collected tongue and pulse of non-small-cell lung cancer patients with Qi deficiency syndrome ( = 163), patients with Yin deficiency syndrome ( = 174), and healthy controls ( = 185) using intelligent tongue diagnosis analysis instrument and pulse diagnosis analysis instrument, respectively. We described the characteristics and examined the correlation of data of tongue and pulse.

[Professor 's experience in treating intractable sudden deafness with acupuncture and moxibustion].

Professor -'s experience and medical record in the treatment of intractable sudden deafness with acupuncture is introduced. Professor believes that this disease is mainly caused by the blockage of meridians, and should be treated with acupuncture therapy as soon as possible. According to the root cause and the pathogenesis of blockage, the method of "soothing , clearing the ear and opening the orifices" is adopted.

[Professor 's clinical experience of acupuncture for oculomotor nerve paralysis].

Professor -'s clinical experience of acupuncture for oculomotor nerve palsy was summarized and one typical case was introduced. Professor skillfully applied traditional acupuncture theory and classical acupuncture method, and proposed a diagnosis and treatment system combining meridian syndrome differentiation and specific acupuncture techniques. In addition, Professor combined the -primary and -connecting acupoints combination method, theory of "removing the stagnation of blood and " and theory of root-stem and origin-end, etc.

[Professor s experience in treatment of progressive muscular dystrophy with acupuncture].

Professor 's experience is introduced in treatment of progressive muscular dystrophy with acupuncture. It is believed that the pathogenesis of this disease is related to spleen and kidney deficiency, and blood insufficiency and malnutrition of tendon and muscle. The treatment is determined in terms of the pathogenesis and focuses on the regulation of spleen and kidney functions.

A retrospective study to compare the treatment outcomes with and without surgical navigation for fracture of the orbital wall.

Purpose: To evaluate the outcomes with and without aid of a computer-assisted surgical navigation system (CASNS) for treatment of unilateral orbital wall fracture (OWF).

Methods: Patients who came to our hospital for repairing unilateral traumatic OWF from 2014 to 2017 were included in this study. The patients were divided into the navigation group who accepted orbital wall reconstruction aided by CASNS and the conventional group.

Toll‑like receptor 4 activates the NLRP3 inflammasome pathway and periodontal inflammaging by inhibiting Bmi‑1 expression.

Overproduction of pro‑inflammatory cytokines in the aged, which is called inflammaging, leads to the deterioration of periodontitis. Toll‑like receptor 4 (TLR4) plays a role in the regulation of cellular senescence, and its expression increases with age. However, there has been limited research into the molecular mechanisms underlying the onset of periodontal inflammaging, and the interplay between TLR4 and inflammaging.

[Professor -'s experience in the new clinical application of Yinjiao (GV 28)].

Yinjiao (GV 28) is generally used in treatment of lumbago and anorectal diseases. Professor - believes that Yinjiao (GV 28) is indicated in the disorders related to the sea of marrow and lower by regulating the governor vessel and the conception vessel, promoting and blood circulation, tonifying the sea of marrow and adjusting the lower . Based on professor 's clinical experience, "three Yinjiao" points are innovated, named Yinjiao (GV 28, upper Yinjiao), external Yinjiao and lower Yinjiao.

miR-597-3p inhibits invasion and migration of thyroid carcinoma SW579 cells by targeting RAB23.

Introduction: Nowadays, it is indicated that miRNA was anomaly expressed in tumour. Previous studies have shown that miRNAs can regulate the proliferation, invasion, and migration of cancer cell-related processes. Meanwhile, current investigations show that RAB23 also plays an important role in cancer cell-related processes.

[Exploration of fire needling therapy on coronavirus disease 2019].

Combined with previous clinical experience in anti-epidemic and acupuncture, the prevention program of fire needling therapy for coronavirus disease 2019 (COVID-19) was drawn out. Fire needling therapy has the effects of clearing heat, removing dampness, replenishing for the deficiency, removing stasis and detoxifying, which is mainly aimed at preventing populations, light and common types cases, and cases in the recovery period. Acupoints of governor vessel, lung meridian, bladder meridian and stomach meridian are mainly used in this program.

Poloxamer modified florfenicol instant microparticles for improved oral bioavailability.

Surfactants can improve the hydrophobicity of poorly water-soluble drugs and increase the stability of microparticles by reducing surface tension. This study describes that surfactant-engineered florfenicol instant microparticles (FIMs) increase bioavailability through a micellar solubilization mechanism. The FIMs were prepared by a modified emulsification method, and the optimal prescription was obtained by a combination of single factor investigation and response surface methodology.

P16 played a critical role in exacerbating acute tubular necrosis in acute kidney injury.

Acute kidney injury (AKI) is a common clinical syndrome with high morbidity and mortality, which is mostly caused by acute tubular necrosis (ATN). AKI is associated with many factors, including cell senescence, inflammatory infiltration, apoptosis and excessive accumulation of reactive oxygen species (ROS). P16 (hereafter termed p16) inhibits cell cycle, and the absence of can significantly slow the progression of cell senescence.