Publications by authors named "Shi-Yong Lu"
Frontal affinity chromatography (FAC) combined with enzyme has been widely used for drug screening. In this paper, the effect of target enzyme activity on screening of bioactive compounds was studied through applying FAC. Trypsin with different degree of inactivation were prepared as target enzyme by thermal denaturation.
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- The study aimed to develop a decoction method for Atractylode macrocephala using ultrasonic waves to enhance the extraction of active components.
- Factors such as material-to-liquid ratio, ultrasonic power, and soaking time were systematically analyzed to identify the optimal extraction parameters through response surface methodology.
- The optimal extraction conditions resulted in an 88.5% retention of active components, establishing ultrasonic extraction as an effective method for this plant.