A solid phase extraction column based on SiO@ZIF-8 for efficient analysis of domoic acid toxins in the seawater environment: experiments and DFT calculations on adsorption behaviour.

Algal toxins are important metabolites of toxic harmful algal blooms (HABs), and their qualitative and qualitative detection can serve as early warning indicators for toxic HABs, complementing traditional HAB monitoring and improving the accuracy of early warning. Therefore, this work took the detection of domoic acid (DA) as an example and prepared zeolitic imidazolate framework-8 (ZIF-8) with high enrichment performance and high water stability and its core-shell composite material SiO@ZIF-8 as an adsorbent filler. Density functional theory (DFT) calculations and interference experiments verified that Zn on SiO@ZIF-8 played a crucial role in enriching DA on SiO@ZIF-8.