Graphene and graphene-based materials in axonal repair of spinal cord injury.

Graphene and graphene-based materials have the ability to induce stem cells to differentiate into neurons, which is necessary to overcome the current problems faced in the clinical treatment of spinal cord injury. This review summarizes the advantages of graphene and graphene-based materials (in particular, composite materials) in axonal repair after spinal cord injury. These materials have good histocompatibility, and mechanical and adsorption properties that can be targeted to improve the environment of axonal regeneration.

Preparation and Evaluation of a Self-Nanoemulsifying Drug Delivery System Loaded with Heparin Phospholipid Complex.

A self-nanoemulsifying drug delivery system (SNEDDS) was developed to enhance the absorption of heparin after oral administration, in which heparin was compounded with phospholipids to achieve better fat solubility in the form of heparin-phospholipid (HEP-Pc) complex. HEP-Pc complex was prepared using the solvent evaporation method, which increased the solubility of heparin in -octanol. The successful preparation of HEP-Pc complex was confirmed by differential scanning calorimetry (DSC), Fourier-transform infrared (FT-IR) spectroscopy, NMR, and SEM.

Targeting the Epithelial-to-Mesenchymal Transition in Cancer Stem Cells for a Better Clinical Outcome of Glioma.

Glioma is one of the most common malignant tumors of the central nervous system with a poor prognosis at present due to lack of effective treatment options. Its initiation, migration, and multipotency are affected by cancer stem cell's transition. Previous studies imply that changes in the cancer stem cells can affect the malignant differentiation of the tumor.

Diagnosis and treatment of novel coronavirus pneumonia based on the theory of traditional Chinese medicine.

Since the outbreak of novel coronavirus pneumonia (coronavirus disease 2019, COVID-19), it has rapidly spread to 187 countries, causing serious harm to the health of people and a huge social burden. However, currently, drugs specifically approved for clinical use are not available, except for vaccines against COVID-19 that are being evaluated. Traditional Chinese medicine (TCM) is capable of performing syndrome differentiation and treatment according to the clinical manifestations of patients, and has a better ability of epidemic prevention and control.

[High Resolution Remote Sensing Monitoring and Assessment of Secondary Geological Disasters Triggered by the Lushan Earthquake].

The secondary geological disasters triggered by the Lushan earthquake on April 20, 2013, such as landslides, collapses, debris flows, etc., had caused great casualties and losses. We monitored the number and spatial distribution of the secondary geological disasters in the earthquake-hit area from airborne remote sensing images, which covered areas about 3 100 km2.

[An analysis of soft tissue profile features of beautiful men and women with polar coordinates].

Purpose: To analyze the profile features of soft tissues of beautiful young men and women with Han nationality by polar coordinates.

Methods: Sixty-two beautiful college students (aged 18-23 years, average 20.1 years, 31 men, 31 women) were chosen according to inclusion criteria as study samples.

Potential anti-HPV and related cancer agents from marine resources: an overview.

Recently, the studies on the prevention and treatment of human papillomavirus (HPV) which is closely related to the cervical cancer and other genital diseases are attracting more and more attention all over the world. Marine-derived polysaccharides and other bioactive compounds have been shown to possess a variety of anti-HPV and related cancer activities. This paper will review the recent progress in research on the potential anti-HPV and related cancer agents from marine resources.

Analysis of ecological quality of the environment and influencing factors in China during 2005-2010.

Since the twentieth century, China has been facing various kinds of environmental problems. It is necessary to evaluate and analyze the ecological status of the environment over China, which is of great importance for environmental protection measures. In this article, an Eco-environmental Quality Index (EQI) model is established using national remote sensing land-use data, NDVI data from MODIS and other statistical data.

[The effect of suppressive oligodeoxynucleotides on interferon-γ and phosphorylation of signal transducers and activators of transcription 4 expression of silica-induced pulmonary inflammation in mice].

Objective: To investigate the protective effect of suppressive oligodeoxynucleotides (Sup ODN) on interferon-γ (IFN-γ) and signal transducers and activators of transcription (pSTAT4) expression of Silica-induced pulmonary inflammation in Mice.

Methods: Sixty Balb/c mice were randomly divided into 4 groups, normal control group, silicious group, suppressive oligodeoxynucleotides (Sup ODN) group, control oligodeoxynucleotides (Con ODN) group. Except the normal control group injected normal saline, the rest groups were induced by the intratracheal instillation of 0.

[Application of urinary proteomics in early diagnosis of bladder urothelial carcinoma].

Objective: To investigate the difference in urinary proteome between patients with bladder urothelial carcinoma (BUC) and healthy volunteers and to provide a basis for the early diagnosis of BUC.

Methods: The urine samples from BUC patients and healthy volunteers (controls) were treated by 25% ethanol precipitation and two-dimensional gel electrophoresis (2-DE), and the obtained urinary proteins were subjected to Coomassie brilliant blue staining and analysis by PDQuest 8.0 (2-DE image analysis software); the differentially expressed proteins were sequenced by matrix-assisted laser desorption/ionization time-of-flight/time-of-flight mass spectrometry and identified using the Swiss-Prot database; the differential expression of these proteins was verified by western blot.

The antiviral activities and mechanisms of marine polysaccharides: an overview.

Recently, the studies on the antiviral activities of marine natural products, especially marine polysaccharides, are attracting more and more attention all over the world. Marine-derived polysaccharides and their lower molecular weight oligosaccharide derivatives have been shown to possess a variety of antiviral activities. This paper will review the recent progress in research on the antiviral activities and the mechanisms of these polysaccharides obtained from marine organisms.

[Effects of Gymnadenia conopse alcohol extract on early protein profiles in lung tissue of rats exposed to silica].

Objective: To analyze the early expression differences of lung tissue proteins in rats exposed to silica using comparative proteomics method, to explore the effects of Chinese traditional medicine (Gymnadenia conopse alcohol extract, GcAE) on silicosis (50 mg/ml).

Methods: Adult male Wistar rats were randomly divided into silica-treated group and GcAE-treated group, four rats a group. The rats were exposed to silica by intratracheal (IT) instillation of 1 ml silica suspension for 24 h.

[Correlation analysis between the exposure levels and the serum protein fingerprints in population exposure to silica].

Objective: To explore the correlation between the exposure levels and serum protein fingerprints in population exposed to silica.

Methods: Liquid chip time-of-flight mass spectrometry technology was used to investigate the serum profiles in control group (30 cases), group exposed to silica (30 cases), silicosis group (I stage, 25 cases) and suspected silicosis group (30 cases), and screen the differential expression proteins. The correlation between the levels of the differential expression proteins and the exposure levels was performed.

[The effects of complement C3f segment on expression and secretion of collagen I, III and transforming growth factor-beta1 in human embryonic lung fibroblast].

Objective: To observe the effects of complement fragment C3f on expression and secretion of collagen I, III and transforming growth factor( TGF)-beta1 in human embryonic lung fibroblast (MRC-5) cells.

Methods: MRC-5 cells were cultured with C3f (the synthetic 17 peptides fragments of complement C3). The extracellular and intracellular expression levels of type I, III collagens and TGF-beta1 in MRC-5 cultures were detected by ELISA and immunohistochemistry, respectively.

[The study of the differential gene expression profiles related to toxic effects in rats exposed to silica].

Objective: To study the differential gene expression profiles related to toxic effects in rats exposed to silica.

Methods: Wistar rats exposed to SiO2 (50 mg/ml) and 1 ml normal saline by intratracheal injection served as the exposure and control groups, on the 14th day after exposure all rats were executed and the rat lung tissues were obtained. The differential gene expression profiles in the lung tissues of rats exposed to silica were detected using confocal fiber beads gene chip technique, and the differential expression profiling data were analyzed using the database for annotation, visualization and integrated discovery (DAVID) bioinformation analysis tool.

[Vegetation water content retrieval and application of drought monitoring using multi-spectral remote sensing].

The vegetation is one of main drying carriers. The change of Vegetation Water Content (VWC) reflects the spatial-temporal distribution of drought situation and the degree of drought. In the present paper, a method of retrieving the VWC based on remote sensing data is introduced and analyzed, including the monitoring theory, vegetation water content indicator and retrieving model.

Snow cover monitoring method by using HJ-1 satellite data.

Environment and Disasters Monitoring Microsatellite Constellation with high spatial resolution, high temporal resolution and high spectral resolution characteristics was put forward by China. HJ-1B satellite, one of the first two small optical satellites, had a CCD camera and an infrared camera, which would provide an important new data source for snow monitoring. In the present paper, through analyzing the sensor and data characteristics of HJ-1B, we proposed a new infrared normalized difference snow index (INDSI) referring to the traditional normalized difference snow index (NDSI).

[Study on the method of recognizing abandoned farmlands based on multispectral remote sensing].

Being abandoned for farmland seriously affected China's grain output for farmlands. It has become an important phenomenon over the past 20 years in China. Multispectral remote sensing has the advantage of wide range and high speed in requiring data.

[Primary study on changes of serum proteomics in rabbit superior mesenteric artery occlusion shock].

Objective: To explor the changes of serum proteomics in rabbits superior mesenteric artery occlusion (SMAO) shock as well as its possible effect in SMAO shock.

Methods: SMAO shock model in rabbits were induced by occlusion of the superior mesenteric artery, serum samples were obtained from rabbits before and after SMAO shock, proteins in samples were separated by two-dimensional electrophoresis(2-DE), spots in the 2-DE map were detected and evaluated by PDQuest software 8.0.

[Investigation and assessment of damage in earthquake in Yushu, Qinghai based on multi-spectral remote sensing].

The devastating Yushu Earthquake occurred in Qinghai Province, northwest China, with a magnitude of 7.1 on April 14, 2010, which has caused huge destructive losses. Most buildings along the seismic zone were ruined, especially the old and the basic civil structure houses completely destroyed.

[Application and prospect of multi-spectral remote sensing in major natural disaster assessment].

After the occurrence of major natural disasters, it is of great significance that disaster states are assessed timely and accurately for decision-making departments to draw up effective response programs. Multi-spectral remote sensing has a great advantage and potential in disaster assessment, with the characteristics of a wide range of data acquisition, high speed, etc. In several major natural disaster assessments in China, multi-spectral remote sensing technology has played an important role.

[Algorithm of inland water retrieval based on spectral matching].

This present paper presents a new inversion method of inland water based on spectral matching. First step of this method is using the known water surface measured hyperspectral and the absorption coefficient of each component, and obtaining backscattering coefficient of suspended matter with bio-optical model. The second step is calculation of the spectral reflectance of water bodies based on bio-optical model, through the cross-combination of inherent optical property of water components (chlorophyll, suspended matter, yellow substance), in order to create a look-up table of Rrs that corresponds to all combinations of water component.