Multiresponsive Vesicles Composed of Amphiphilic Azacalix[4]pyridine Derivatives.

Biomimicry of multiresponsive recognition of cell membrane with artificial membranes is challengeable. In this work, we designed azacalix[4]pyridine-based amphiphilic molecules 1 and 2. The self-assembly behaviors of 1 and 2 were investigated in aqueous medium.

Liquid crystalline macrocyclic azacalix[4]pyridine and its complexes with the zinc ion: conformational change from the saddle to flattened shape.

Substituted with four 3,4,5-tris(alkoxy)benzyl mini-dendrons, azacalix[4]pyridine (1) with the saddle-shaped core is the first liquid crystal (LC) of heteracalixaromatics. Conformational regulation of azacalix[4]pyridine by complexing with the zinc ion leads to a significant change in LC properties.

Synthesis, structure, and fullerene-complexing property of azacalix[6]aromatics.

Synthesis, structure, and fullerene-binding property of azacalix[6]aromatics were systematically studied. By means of [3 + 3] and [2 + 2 + 2] fragment coupling protocols, a number of azacalix[6]aromatics containing different combinations of benzene, pyridine, and pyrimidine rings and various substituents on the bridging nitrogen atoms were synthesized conveniently in moderate to good yields. The resulting macrocycles adopt in the solid state symmetric and heavily distorted 1,3,5-alternate conformations depending on the aromatic building units, whereas, in solution, they exist as a mixture of conformers that undergo rapid interchanges relative to the NMR time scale.

Anion-directed assembly of a rectangular supramolecular cage in the solid state with electron-deficient phenoxylated oxacalix[2]arene[2]triazine.

Chloride-π interaction along with lone-pair electrons-π interaction, hydrogen bonding and π-π stacking induced the hexameric assembly of the parent macrocycle into a rectangular supramolecular cage in the solid state.

Synthesis and structure of oxacalix[2]arene[2]triazines of an expanded π-electron-deficient cavity and their interactions with anions.

Novel macrocyclic anion receptors based on the principle of anion-π interactions were reported. By means of both post-macrocyclization modification protocol and the stepwise fragment coupling approach, functionalized oxacalix[2]arene[2]triazines bearing two other electron-deficient (hetero)aromatic rings on the lower rim were efficiently synthesized. The resulting oxacalix[2]arene[2]triazine macrocyclesadopt 1,3-alternate conformation, yielding therefore an expanded electron-deficient cavity or space consisting of two triazine rings and two appending aromatic rings.