Covalent Organic Framework-Based Nanomotor for Multimodal Cancer Photo-Theranostics.

Developing efficient integrated diagnosis and treatment agents based on fuel-free self-movement nanomotors remains challenging in antitumor therapy. In this study, a covalent organic framework (COF)-based biomimetic nanomotor composed of polypyrrole (PPy) core, porphyrin-COF shell, and HCT116 cancer cell membrane coating is reported. Under near-infrared (NIR) light irradiation, the obtained mPPy@COF-Por can overcome Brownian motion and achieves directional motion through self-thermophoretic force generated from the PPy core.

[Meta-analysis of the role of two common prostheses in total hip replacement].

Objective: To systematically review the role of two common prostheses(metal on metal and metal on polythene)in total hip replacement.

Methods: Studies on two prostheses(metal on metal and metal on polythene)in total hip replacement were searched in databases including PubMed, EMBASE, the Cochrane library, CNKI database, WANFANG database, and VIP database using key words including"metal on metal", "metal on polythene", and "total hip replacement". Meta-analysis was performed using RevMan 5.