Occlusion of Bilobulated Left Atrial Appendage Using the Dual-Watchman Technique: A Long-Term Follow-Up Study.

Background: Percutaneous left atrial appendage (LAA) occlusion has been considered an efficient alternative to oral anticoagulation to prevent embolic events in patients with non-valvular atrial fibrillation (NVAF). Due to the complexities and heterogeneous anatomy of the LAA structure, the single-device approach may not always fit a large bilobulated LAA. This study aimed to evaluate the feasibility and safety of one-stop dual Watchman implantation for patients with bilobulated LAA.

Surface behavior of a model surfactant: a theoretical simulation study.

A quantum mechanics (QM) method has been used to calculate molecular properties of sodium dodecylbenzenesulfonate (SDBS) in vacuum and in solution. Furthermore, molecular dynamics (MD) simulations have been used to determine the dynamic behavior of SDBS moving from the bulk solution to the air/water interface. QM calculations suggest that two head-group oxygen atoms on each surfactant molecule interact with a Na(+) ion, despite the availability of three oxygen atoms in the head group.