Publications by authors named "Shi-Min Xie"

Article Synopsis
  • CHRDL1 is a newly identified mRNA that potentially influences oral squamous cell carcinoma (OSCC), but its specific functions and mechanisms are still unclear.
  • Research utilized various techniques like RT-qPCR and immunohistochemistry to examine how the MED29 gene expression relates to OSCC progression and cellular behaviors like migration and invasion.
  • Results showed that increased MED29 levels in tumor tissues promote epithelial-mesenchymal transition (EMT) and cancer cell movement, while CHRDL1 suppresses MED29, thus inhibiting OSCC cell invasion and metastasis.
View Article and Find Full Text PDF

The infections caused by Herpes simplex viruses (HSV-1 and -2) are seriously endangering the health of all human beings. Once infected with these two viruses, it will cause life-long latency in the host, and the continuous recurrence of the infection will seriously affect the quality of life. Moreover, infections with HSV-1 and HSV-2 have been reported to make the body susceptible to other diseases, such as Alzheimer's disease and HIV.

View Article and Find Full Text PDF

Ixeris sonchifolia (IS), principally its dried form, is widely used as traditional and folk medicines in some Asian countries, especially China. In this review, we summarized its traditional uses, chemical constituents, quality control measures, pharmacological activities, therapeutic evaluation, toxicity evaluation and clinical applications. 130 chemical constituents isolated from IS have been reported, including flavones, sesquiterpenes, triterpenes, phenylpropanoids, organic acids and others.

View Article and Find Full Text PDF

We prepared octreotide (OCT)-modified curcumin plus docetaxel micelles to enhance active targeting and inhibit tumor metastasis by destroying vasculogenic mimicry (VM) channels. Soluplus was applied as an amphiphilic material to form micelles via film dispersion. The cytotoxic effects, active cellular targeting, and inhibitory effects on metastasis were systematically evaluated using A549 cells, and antitumor effects were evaluated using xenograft tumor-bearing mice.

View Article and Find Full Text PDF