Publications by authors named "Shi-Lin Liu"
[Blinatumomab as bridging therapy in two children with B-cell acute lymphoblastic leukemia complicated by invasive fungal disease].
Zhongguo Dang Dai Er Ke Za Zhi
December 2023
This article reports two cases of children with B-cell acute lymphoblastic leukemia (B-ALL) complicated by invasive fungal disease (IFD) who received bridging treatment using blinatumomab. Case 1 was a 4-month-old female infant who experienced recurrent high fever and limb weakness during chemotherapy. Blood culture was negative, and next-generation sequencing (NGS) of peripheral blood, bronchoalveolar lavage fluid, and cerebrospinal fluid were all negative.
View Article and Find Full Text PDF[Prognostic Factors Analysis of Children with Hemophagocytic Lymphohistiocytosis].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2021
Objective: To analyze the risk factors affecting prognosis of children with hemophagocytic lymphohistiocytosis (HLH).
Methods: The clinical manifestations and laboratory data of 143 HLH children who met the HLH-2004 diagnostic criteria in Shenzhen Children's Hospital from January 2009 to May 2017 were retrospectively analyzed, and the independent factors affecting prognosis were also analyzed.
Results: The median age of 143 HLH children was 1.
Article Synopsis
- - The study aimed to assess the prevalence of allergic rhinitis (AR) and its risk factors among preschool children in Beijing, using a two-stage random sampling method with a large parent survey and subsequent examinations.
- - Results showed a high prevalence of epidemiologic AR at 48%, with urban areas having higher rates compared to suburban areas, and confirmed clinical AR in 14.9% of children, where common allergens included Alternaria tenuis and various dust mites.
- - The findings indicate that AR is prevalent in young children, is influenced by environmental factors, and is associated with higher occurrences of asthma and eczema, suggesting a need for better awareness and management strategies.
[A clinical study of paradoxical breathing during sleep in children].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
September 2010
Objective: Abnormal breathing during sleep included many patterns. In this study, we investigated paradoxical breathing patterns during sleep in children using standard polysomnography (PSG).
Methods: Children who come to the ENT because of snoring were included into the study consecutively.
[Diagnostic procedures for pediatric otitis media with effusion].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
December 2008
Article Synopsis
- The study aimed to evaluate the fluid present in the middle ear of patients with otitis media with effusion (OME) using tympanometry and hearing thresholds, to improve treatment strategies.
- It involved 40 patients (75 ears) between January 2007 and June 2008, finding that 82.7% had fluid present in the middle ear, with all tympanometry results showing type "B."
- The findings suggest a significant correlation between hearing loss levels, CT results, and fluid presence, indicating the need for better diagnostic methods using tympanometry and hearing threshold.
[The mechanism of prophylactic effects of nasal tolerance with a dual analogue on experimental autoimmune myasthenia gravis in young mice].
Zhongguo Dang Dai Er Ke Za Zhi
April 2008
Objective: To study the prophylactic effects of nasal tolerance with a dual analogue, Lys262-Ala207, on the mouse model of experimental autoimmune myasthenia gravis (EAMG) and the underlying mechanism.
Methods: Mouse model of EAMG was induced by intraperitoneal injection of mAb35. Lys262-Ala207 or PBS was given nasally before 10 days (study group A and control group A) or on the day (study group B and control group B) of immunization for 10 days.
[Comparison of the low and high frequency tympanometries as diagnostic tests of middle ear function in infants].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
May 2006
Article Synopsis
- - The study assessed how effective low frequency (226 Hz) and high frequency (678 Hz, 1000 Hz) tympanometry is for diagnosing middle ear function in infants aged 5-25 weeks.
- - Results showed that 1000 Hz tympanometry provided a high level of consistency with auditory brainstem response (ABR) results, making it a reliable diagnostic tool, whereas 226 Hz and 678 Hz did not show significant differences or reliability in this context.
- - The findings suggest that using 1000 Hz is more accurate for detecting middle ear issues in young infants with normal or prolonged ABR wave latency.
[Influence of obstructive sleep apnea-hypopnea syndrome in children on hearing problem].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
September 2005
Article Synopsis
- The study investigates how obstructive sleep apnea (OSA) affects hearing in children, focusing on 143 children diagnosed with sleep apnea through polysomnography.
- Testing included pure tone audiometry, acoustic impedance measurement, and X-ray for nasal airway assessment.
- Findings revealed that many children had abnormal tympanograms and elevated hearing thresholds, with potential improvements in hearing levels following surgeries like adenoidectomy or adenotonsillectomy.
[A study of high altitude environment affecting on worker's health during the constructing Qinghai-Xizang railway].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
February 2004
Objective: To study high altitude environment affecting on worker's health
Methods: Using the cohort study, the altitude reaction was investigated and the WBC, RBC, Hb and oxygenation indexes were measured on workers in several periods, namely, acclimatization period, initially arrived high altitude and resident 90 days.
Results: The 83.3% of men had altitude reactions with different kinds at initially arrived high altitude.