Manipulation of crystallization nucleation and thermal degradation of PLA films by multi-morphologies CNC-ZnO nanoparticles.

Currently, the quest for more renewable and biodegradable materials is a scientific priority to address the problems of petroleum-based plastics are difficult to degrade. In this work, cellulose nanocrystals (CNC) have been used as a template and four morphologies of CNC-ZnO nanocomposites were prepared via a hydrothermal method, and CNC-ZnO/polylactic acid (PLA) composite films were obtained by solution casting. We find that CNC-ZnO nanocomposites as heterogeneous nucleating agents improved the crystallinity and the film with flower-like CNC-ZnO was improved by 2.

Inhibition of Heat Shock Protein 90 as a Novel Platform for the Treatment of Cancer.

Heat shock protein 90 (Hsp90) plays an essential role in various physiological and pathological processes. It activates client proteins to participate in tumor progression. Blocking Hsp90 could enable effective antitumor effects in many tumor types, such as multiple myeloma and colon cancer.

[5-(Pyridin-2-yl)-1H-tetra-zole-κ(2) N (4),N (5)]bis(triphenyl-phosphane-κP)copper(I) tetra-fluoridoborate.

In the title Cu(I) compound, [Cu(C6H5N5)(C18H15P)2]BF4, the Cu(I) cation is N,N'-chelated by a 5-(pyridin-2-yl)-1H-tetra-zole ligand and coordinated by two triphenyl-phosphane ligands in a distorted tetra-hedral geometry. The tetra-zole and pyridine rings are essentially coplanar [dihedral angle = 4.1 (3)°].

Tetra-aqua-bis-(6-chloro-pyridine-3-carboxyl-ato-κO)cobalt(II) tetra-hydrate.

In the title compound, [Co(C(6)H(3)ClNO(2))(2)(H(2)O)(4)]·4H(2)O, the Co(II) cation is located on an inversion center and is coordinated by four water mol-ecules and two 6-chloro-pyridine-3-carboxyl-ate anions in a slightly distorted octa-hedral geometry. In the crystal, complex mol-ecules and lattice water mol-ecules are linked by O-H⋯O and O-H⋯N hydrogen bonds into a three-dimensional network.

Bromidotricarbon-yl[2-(pyridin-2-yl-κN)-5-p-tolyl-1,3,4-oxadiazole-κN]rhenium(I) dichloro-methane monosolvate.

In the title compound, [ReBr(C(14)H(11)N(3)O)(CO)(3)]·CH(2)Cl(2), the coordination geometry of the Re(I) atom is a distorted ReC(3)N(2)Br octa-hedron with the carbonyl C atoms in a fac arrangement. Within the 2-(pyridin-2-yl)-5-p-tolyl-1,3,4-oxadiazole ligand, the dihedral angles between the oxadiazole ring and the pyridine (py) and benzene (bz) rings are 1.7 (2) and 7.

Bromidotricarbon-yl[2-phenyl-5-(pyridin-2-yl-κN)-1,3,4-oxadiazole-κN]rhenium(I) dichloro-methane monosolvate.

In the title rhenium(I) complex, [ReBr(C(13)H(9)N(3)O)(CO)(3)]·CH(2)Cl(2), the dichloro-methane solvent mol-ecule is disordered over two positions with an occupancy ratio of 0.81 (15):0.19 (15).