Publications by authors named "Shi-Kang Chen"
Bacterial infection severely hinders skin wound healing, highlighting the critical application value of developing antibacterial and anti-inflammatory hydrogel dressings. In this work, we focused on β-glucan from Hericium erinaceus (HEBG) as the research object, and proposed a solvent-induced combined temperature manipulation technique to trigger multilevel self-assembly of β-glucan. Furthermore, we incorporated green synthesized near-infrared photosensitizer tannic acid (TA)/iron (III) complex into the system.
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- Natural fungal β-glucans, particularly those from Hericium erinaceus, possess unique structures that enable immunomodulation and anti-inflammatory effects, which can be harnessed for therapeutic uses.
- The study developed a hydrogel (HEBG/TA) by combining β-glucan with tannic acid, resulting in an injectable material with enhanced antioxidant properties and the ability to manage temperature-responsive drug release.
- In vivo tests on wound healing showed that this hydrogel significantly improved tissue regeneration, reduced inflammation, and promoted angiogenesis, making it a promising candidate for skin repair treatments.
Article Synopsis
- The study examined the physicochemical properties and structural characteristics of polysaccharides from the mushroom Agrocybe cylindracea at four growth stages.
- Researchers found that although there was a significant drop in polysaccharide yields as the mushroom matured, the overall structural features remained similar across the stages.
- Notably, the study identified various polysaccharides, including a new type—glucuronofucogalactoglucan—and highlighted changes in their structure during maturation, which could have applications in the food and biomedicine sectors.
Polysaccharides derived from have been demonstrated to exhibit various bioactivities. However, studies on their structural characteristics during the growth process are limited. This study aimed to compare the physicochemical properties and structural characteristics of alkali-extracted polysaccharides from fruiting bodies (JACP) across four growth stages.
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- Polysaccharides are common organic compounds with complex structures, and understanding their order and disorder is challenging.
- This study used techniques like FT-IR, methylation analysis, and H NMR spectroscopy to evaluate the structural order of polysaccharides from various regions, identifying four main structural types with specific glycoside linkages.
- The findings support a theoretical framework for classifying polysaccharide structures, revealing key characteristics of heteroglucans and heterogalactans that help simplify their complexity.
Exploring the partial degradation of polysaccharides: Structure, mechanism, bioactivities, and perspectives.
Compr Rev Food Sci Food Saf
November 2023
Polysaccharides are promising biomolecules with lowtoxicity and diverse bioactivities in food processing and clinical drug development. However, an essential prerequisite for their applications is the fine structure characterization. Due to the complexity of polysaccharide structure, partial degradation is a powerful tool for fine structure analysis, which can effectively provide valid information on the structure of backbone and branching glycosidic fragments of complex polysaccharides.
View Article and Find Full Text PDFIn this study, ten pea ( L.) varieties were compared in their nutrient composition, phenolic compounds, antioxidant properties and their diversity were deciphered by multivariate analysis of correlation analysis and principal component analysis (PCA). The ten pea cultivars are rich in nutrients with different contents in lipid (0.
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