Publications by authors named "Shi-Jie Na"

Article Synopsis
  • Intracranial hemorrhage poses a significant risk with standard-dose ticagrelor in dual antiplatelet therapy for patients with unruptured intracranial aneurysms, leading researchers to explore a lower dose.
  • A study compared the effects of half-dose ticagrelor and standard-dose clopidogrel in patients undergoing stent-assist coiling or flow diversion, measuring platelet aggregation and adverse events over six months.
  • The results showed that half-dose ticagrelor had comparable antithrombotic effects and safety profiles to clopidogrel, suggesting it could be a viable alternative in managing these patients.
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Background: Oculomotor nerve palsy (ONP) may result from posterior communicating artery (PcomA) aneurysms. We aimed to evaluate the resolution of ONP after endovascular treatment with the intention of clarifying predictors of nerve recovery in a relatively large series.

Methods: A total of 211 patients with ONP caused by PcomA aneurysms underwent endovascular coiling between May 2010 and December 2020 in four tertiary hospitals.

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To evaluate the efficacy of liquid embolization agents for treating various hemorrhagic peripheral intracranial aneurysms. We retrospectively analyzed 38 patients who suffered from hemorrhagic peripheral intracranial aneurysms and were treated with liquid embolization agents. We used the modified Rankin scale for follow-up at 6 months postoperatively, and digital subtraction angiography follow-up was performed 6 months postoperatively.

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Background: Agitation is common in subarachnoid hemorrhage (SAH), and sedation with midazolam, propofol and dexmedetomidine is essential in agitation management. Previous research shows the tendency of dexmedetomidine and propofol in improving long-term outcome of SAH patients, whereas midazolam might be detrimental. Brain metabolism derangement after SAH might be interfered by sedatives.

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Cerebral metabolism alterations influence cerebrospinal fluid (CSF) composition and are sensitive to brain injury. In subarachnoid hemorrhage (SAH) patients, Fisher scale, Hunt-Hess scale, and World Federation of Neurological Societies (WFNS) grading scale evaluating SAH severity are inadequate to predict long-term outcome; therefore, in an effort to determine metabolite pattern disparity and discover corresponding biomarkers, we designed an untargeted CSF metabolomic study covering a broad range of metabolites of SAH patients with different severity and outcome. The present study demonstrated the SAH altered the cerebrospinal fluid metabolome involving carbohydrate, lipid, and amino acid metabolism.

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Article Synopsis
  • The study looks at patients who have narrowed blood vessels in the brain (intracranial stenosis) and unbroken bulges (aneurysms).
  • Two groups were created: one got a special treatment (angioplasty and embolization) and the other did not.
  • The group that received treatment had no strokes or deaths, but the other group lost two patients due to a brain bleed, showing different outcomes based on the treatment.
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