Publications by authors named "Shi-Ji Zhou"

Article Synopsis
  • The study investigates how cirrhosis influences the progression of hepatocellular carcinoma (HCC) by comparing the long noncoding RNAs (lncRNAs) expressed in cirrhotic HCC (CHCC) versus noncirrhotic HCC (NCHCC).
  • Researchers identified a specific lncRNA called DERCNC, which is found to be significantly elevated in CHCC, correlating with worse tumor prognoses and increased tumor proliferation.
  • The study concludes that DERCNC promotes tumor growth by upregulating the SOX9 gene, revealing a new pathway through which cirrhosis may enhance cancer progression.
View Article and Find Full Text PDF

Ex-situ stabilization for As and Sb co-contaminated soil was conducted through an iron-based stabilizer, PFSC (a mixture of polymerized ferric sulfate (PFS) and hydrated lime (Ca(OH)) with a dry mass ratio of 2:1). After field aging for one week, the stabilized contaminated soil was subjected to a horizontal vibration leaching test (HJ 557), Wenzel's sequential extraction, and a semi-dynamic leaching test (ANS 16.1).

View Article and Find Full Text PDF

Compacted clay covers (CCCs) are effective in restricting the upward migration of volatile organic compound (VOC) and semi-volatile organic compound (SVOC) vapors released mainly from unsaturated contaminated soils and hence mitigate the risks to human health. Desiccation cracking of CCCs would result in numerous preferential channels. VOC or SVOC vapors can prefereially migrate through the cracks and emit into the atmosphere, exposing threats to human health and surrounding environmental acceptors.

View Article and Find Full Text PDF

This paper presents a study on utilizing a novel BCP binder, basic oxygen furnace slag (BOFS) activated with mixed calcium carbide residue (CCR) and phosphogypsum (PG), to solidify/stabilize heavy metals in industrial contaminated site soil. The effects of curing time and binder dosage on the geoenvironmental properties of the solidified/stabilized soil including soil pH, electrical conductivity, unconfined compressive strength, and leachability were tested and discussed. Chemical speciation of target heavy metals, pore-size distribution of treated soil, and phase identification of reaction products were analyzed to understand the mechanisms leading to the change of geoenvironmental properties.

View Article and Find Full Text PDF

Aim: To evaluate the prognostic value of the number of retrieved lymph nodes (LNs) and other prognostic factors for patients with distal cholangiocarcinomas, and to determine the optimal retrieved LNs cut-off number.

Methods: The Surveillance, Epidemiology and End Results database was used to screen for patients with distal cholangiocarcinoma. Patients with different numbers of retrieved LNs were divided into three groups by the X-tile program.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates how high-intensity focused ultrasound (HIFU) combined with herpes simplex virus thymidine kinase (HSV-TK) gene-loaded microbubbles affects liver tumors in rabbits.
  • Seventy-five rabbits with VX2 liver tumors were divided into different treatment groups to evaluate the effectiveness of these therapies on tumor reduction and cell death.
  • Results showed that the combination of HIFU, HSV-TK, and microbubbles led to the highest levels of gene expression and tumor cell apoptosis, indicating that this approach is potentially more effective than the others tested.
View Article and Find Full Text PDF

Background: The management of hepatolithiasis combined with intrahepatic cholangicarcinoma (IHHCC) remains a challenge due to poor prognosis. The aim of this study was to summarize our diagnosis and cure experience of IHHCC over the recent 10 years.

Methods: From January 1996 to January 2006, 66 patients with IHHCC were reviewed retrospectively.

View Article and Find Full Text PDF

Objective: To observe the effect of ultrasound microbubble carrying herpes simplex virus thymidine kinase hepatocellular carcinoma in mice.

Methods: Kunming mice were inoculated subcutaneously with H22 tumor cells. 40 male mice bearing subcutaneous hepatoma were randomized into 4 groups: PBS (group A), HSV1-TK (group B), HSV1-TK (group C), and microbubble carrying HSV1-TK (group D) were injected into the tail vein every 3 days.

View Article and Find Full Text PDF