Publications by authors named "Shi-Hao Huang"

Objectives: To explore the short- and long-term effects of glycemic management-through glycemic treatment and blood glucose monitoring (BGM)-on stroke recurrence and mortality specifically in patients experiencing a first-ever ischemic stroke (FIS) with hyperglycemia (FISHG) who have not previously been diagnosed with diabetes mellitus (DM).

Methods: We gathered data on patients who were registered on Taiwan's National Health Insurance Research Database from 2000 to 2015. We one-fold propensity-score-matched (by sex, age, and index date) 207,054 patients into 3 cohorts: those with FIS (1) without hyperglycemia, (2) hyperglycemia without glycemic treatment, and (3) hyperglycemia with glycemic treatment.

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  • * Researchers used data from various health monitoring systems to identify trends in outpatient visits, with daily cases ranging from 10 to 7600, and found the coxsackie A virus to be the most common strain.
  • * Significant increases in specific EV strains were noted in certain years, revealing that changes in virus prevalence and outbreak clusters occurred over the decade.
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  • The study systematically reviews and analyzes the effectiveness and safety of psychedelics (psilocybin, ayahuasca, LSD, MDMA) in treating mental disorders based on 126 articles.
  • Results indicate that psilocybin is the most researched and effective psychedelic for mood disorders, with the strongest therapeutic effects, followed by ayahuasca, MDMA, and LSD.
  • While there are some risks, like headaches, most participants reported no lasting adverse effects, suggesting psychedelics may also help with various other mental health issues like addiction and PTSD.
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  • Scientists are studying how heat treatment (hyperthermia) can help fight nasopharyngeal cancer (NPC) and why some cancer cells resist the heat.
  • They found that using heat with a drug called oridonin makes cancer cells easier to kill, especially the tough ones that don't respond well to regular treatments.
  • The study also discovered that a protein called Cirbp helps cancer cells survive heat, and reducing Cirbp improves the effectiveness of heat treatment against these cancer cells.
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Background: The prevalence of oral diseases among Taiwanese prisoners has rarely been investigated. This study aimed to estimate the gender-specific prevalence of oral disease in a sample of Taiwanese prisoners.

Methods: We included 83,048 participants from the National Health Insurance (NHI) Program.

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  • Researchers studied survival chances for Chinese kids with a type of liver cancer called hepatoblastoma and looked at a new treatment from 2016.
  • They found that most kids (93.5%) survived well after four years, and younger kids or those without advanced cancer had the best chances.
  • The results showed that if kids had a big drop in a specific blood marker, they tended to do even better after treatment.
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The sterilisation of surgical instruments is a major factor in infection control in the operating room (OR). All items used in the OR must be sterile for patient safety. Therefore, the present study evaluated the effect of far-infrared radiation (FIR) on the inhibition of colonies on packaging surface during the long-term storage of sterilised surgical instruments.

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B-cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) is overexpressed in various cancer types. We found that mRNA levels were elevated in nasopharyngeal carcinoma (NPC) cell lines. In immunohistochemical analyses, high Bmi-1 levels were observed in not only 5 of 38 non-cancerous nasopharyngeal squamous epithelial biopsies, but also in 66 of 98 NPC specimens (67.

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Objective: Past vegetarians research has often found that they have lower blood pressure (BP). Effects may include their lower BMI and higher intake levels of fruit and vegetables. Besides, the study pursues to extend this evidence in a diverse population containing vegans, lacto-ovo vegetarians and omnivores.

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This study aimed to understand the distribution of the standardized rate of hospitalization for violent injuries in counties and cities in Taiwan. The ICD-9 diagnosis code N-codes 995.5 (abused child) and 995.

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  • Botulinum toxin is produced by the bacterium Clostridium botulinum, and a study analyzed confirmed botulism cases in Taiwan from 2003 to 2020, looking at various epidemiological factors like sex, age, season, and location.
  • The study identified 50 confirmed domestic botulism cases with a decreasing trend over the years, peaking in 2008 and 2010, and most patients were females aged 50 or older in northern Taiwan.
  • Notably, there was an increase in botulism cases among children (particularly boys) from 2010 to 2020, with most infections occurring in spring and summer, marking a significant shift from previous years when no cases were
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To investigate whether previous exposure to obstructive sleep apnea (OSA) increases the risk of obesity in obese and nonobese patients. We identified 24,363 obese patients diagnosed between January 1, 2000, and December 31, 2015, in the Taiwan Longitudinal Health Insurance Database (LHID) 2005 National Health Insurance Research Database; 97,452 sex-, age- and index date-matched nonobese patients were identified from the same database. This study is based on the ninth edition of the International Classification of Sleep Disorders.

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Intestinal infectious diseases (IIDs) are among the most common diseases and are prevalent worldwide. IIDs are also one of the major disease groups with the highest incidence worldwide, especially among children and older adults. We observed a higher probability of IIDs in patients from the psychiatric department of Tri-Service General Hospital.

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Autophagy is crucial for maintaining cellular energy homeostasis and for cells to adapt to nutrient deficiency, and nutrient sensors regulating autophagy have been reported previously. However, the role of eiptranscriptomic modifications such as mA in the regulation of starvation-induced autophagy is unclear. Here, we show that the mA reader YTHDF3 is essential for autophagy induction.

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Objective: To understand the risk of developing a poor prognosis in adulthood after violent injury in Taiwan. Methods: This study used the data of outpatients, from emergency departments, and from hospitalization of 2 million people under National Health Insurance from 2000 to 2015. The ICD-9 diagnostic code N-code was defined as the case of this study and was 995.

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This study aims to understand the trend distribution of violent injuries in Taiwan from 2000 to 2015. It used the data of outpatient, emergency, and hospitalization of 2 million people in the National Health Insurance sample from 2000 to 2015. We analyzed children and adolescents (hereinafter referred to as children, 0-17 years old), adults (18-64 years old), and The Elderly (over 65 years old) who suffered for the first time.

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This study aimed to investigate not only the differences in in-hospital deaths between male and female homicides in Taiwan from 1998 to 2015, but also the epidemiological characteristics and long-term trend analysis. We collected data on 76,125 hospitalized patients injured in attempted homicides from January 1, 1998, to December 31, 2015, from the National Health Insurance Research Database (NHIRD), identifying 59,161 male and 16,694 female patients. Age, gender, and index date match.

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Background: This research focused on the association between physical activity and fruit-vegetable intake and the risk of depression in middle aged and older Taiwanese adults.

Methods: Data were obtained from the 1999 to 2015 datasets of the Taiwan Longitudinal Survey on Aging (TLSA), and 4400 participants were included in 1999 (aged ≥53 years). Descriptive statistics provided all of the basic characteristic variables.

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  • Researchers successfully reprogrammed mouse embryonic fibroblasts into induced pluripotent stem cells (iPSCs) using four key factors: Oct4, Sox2, c-Myc, and Klf4, creating a specific mouse iPSC line (Oct4-GFP miPSCs).
  • The Oct4-GFP miPSCs exhibited characteristics similar to murine embryonic stem cells (mESCs), including comparable morphology, gene expression, and the ability to differentiate into various cell types.
  • This study establishes a foundation for future work on reprogramming human cancer cells into iPSCs and introduces a real-time monitoring system for tracking pluripotency changes using GFP expression.
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This study explored whether atrial fibrillation (AF)’s influence on short sleep duration (SD) increases the subsequent risk of fatness in management executives. This study included 25,953 healthy individuals working as management executives with ages ranging from 35 to 65 years (19,100 men and 6853 women) who participated in a qualifying physical filter program from 2006 to 2017 in Taiwan. Men and women who slept < 4 h had a 4.

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Objective: To identify the differential patient characteristics, injury types, and treatment outcomes between hospitalized child abuse and non-child abuse injuries in Taiwan. Methods: Using the data from the National Health Insurance Research Database, we selected a total of 1525 patients under the age of 18 that were diagnosed with child abuse, as well as an additional 6100 patients as a comparison group. Chi-square test, Fisher exact test, and independent samples t-test were used to compare the differences between the abused children and the non-abuse-related injured children.

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