Transcriptome Analysis and RNA Interference Reveal Regulating Cotton Resistance to Verticillium Wilt by JA and SA Signaling Pathways.

Verticillium wilt, caused by , is one of the most damaging and widespread soil-borne cotton diseases. The molecular mechanisms underlying the cotton defense against remain largely elusive. Here, we compared the transcriptional differences between Upland cotton cultivars: one highly resistant (HR; Shidalukang 1) and one highly susceptible (HS; Junmian 1).

The Cotton Lignin Biosynthetic Gene Regulates Lignification and Phenolic Content and Contributes to Verticillium Wilt Resistance.

Verticillium wilt is a vascular disease causing tremendous damage to cotton production worldwide. However, our knowledge of the mechanisms of cotton resistance or susceptibility to this disease is very limited. In this study, we compared the defense transcriptomes of cotton () cultivars Shidalukang 1 ( resistant, HR) and Junmian 1 ( susceptible, HS) before and after infection, identified hub genes of the network associated with responses to infection, and functionally characterized one of the hub genes involved in biosynthesis of lignin and phenolics.

Corrigendum: Regulates Resistance to in Cotton Through the Ethylene and Jasmonic Acid Signaling Pathways.

[This corrects the article DOI: 10.3389/fpls.2020.

Characterization of the Gh4CL gene family reveals a role of Gh4CL7 in drought tolerance.

Background: The function of 4-coumarate-CoA ligases (4CL) under abiotic stresses has been studied in plants, however, limited is known about the 4CL genes in cotton (G. hirsutum L.) and their roles in response to drought stress.

Juglanin alleviates bleomycin-induced lung injury by suppressing inflammation and fibrosis via targeting sting signaling.

Idiopathic pulmonary fibrosis (IPF), characterized by excessive collagen deposition, is a progressive and typically fatal lung disease without effective therapeutic strategies. Juglanin, as a natural product mainly isolated from green walnut husks of Juglans mandshuric, has various bioactivities, including anti-oxidative, anti-inflammatory and anti-fibrotic effects. Stimulator of interferon genes (Sting) is a signaling molecule and plays an essential role in meditating fibrosis.

GhWRKY70D13 Regulates Resistance to in Cotton Through the Ethylene and Jasmonic Acid Signaling Pathways.

wilt caused by is a destructive cotton disease causing severe yield and quality losses worldwide. WRKY transcription factors play important roles in plant defense against pathogen infection. However, little has been reported on the functions of WRKYs in cotton's resistance to .

Depletion of perineuronal nets in the amygdala to enhance the erasure of drug memories.

Extinction therapy has been suggested to suppress the conditioned motivational effect of drug cues to prevent relapse. However, extinction forms a new inhibiting memory rather than erasing the original memory trace and drug memories invariably return. Perineuronal nets (PNNs) are a specialized extracellular matrix around interneurons in the brain that have been suggested to be a permissive factor that allows synaptic plasticity in the adolescent brain.

Differential role of Rac in the basolateral amygdala and cornu ammonis 1 in the reconsolidation of auditory and contextual Pavlovian fear memory in rats.

Rationale And Objectives: A conditioned stimulus (CS) is associated with a fearful unconditioned stimulus (US) in the traditional fear conditioning model. After fear conditioning, the CS-US association memory undergoes the consolidation process to become stable. Consolidated memory enters an unstable state after retrieval and requires the reconsolidation process to stabilize again.

Functional impact of the hyperpolarization-activated current on the excitability of myelinated A-type vagal afferent neurons in the rat.

1. The hyperpolarization-induced, cation-selective current I(h) is widely observed in peripheral sensory neurons of the vagal and dorsal root ganglia, but the peak magnitude and voltage- and time-dependent properties of this current vary widely across afferent fibre type. 2.