Publications by authors named "Shi-Bin Cao"
Hereditary spherocytosis (HS) is often misdiagnosed due to lack of specific diagnostic methods. Our study summarized clinical characteristics and described the diagnostic workflow for mild and moderate HS in Chinese individuals, using data from 20 adults, 8 of whom presented a familial history for HS. We used scanning electron microscopy (SEM) to diagnose HS.
View Article and Find Full Text PDF[Detection of molecular cytogenetic abnormalities in 30 patients with chronic lymphocytic leukemia by fluorescence in situ hybridization].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
February 2009
Article Synopsis
- The study aimed to explore the effectiveness of interphase fluorescence in situ hybridization (FISH) for identifying gene abnormalities related to chronic lymphocytic leukemia (CLL), focusing on specific genetic deletions and trisomies.
- Out of 30 patients, 63.3% exhibited molecular cytogenetic abnormalities, with the most common being the deletion of the 13q14 region and trisomy of chromosome 12.
- Although no significant links were found between these genetic abnormalities and most clinical factors, a higher incidence of atm gene deletion was noted in patients with high CD38 expression, indicating the need for further research into the prognostic implications of these findings.