Publications by authors named "Shi Weiyi"

To inhibit eutrophication caused by endogenous pollutants release, the experiment explored the efficiency and mechanism of the synchronous control of nitrogen (N) and phosphorus (P) release from sediments in shallow lakes under wind disturbance by modified Ca/Al-based sludge (MS) and modified zeolite (MZ). High-temperature calcination and NaCl impregnation increased the pore volume of MS and Na content of MZ, and the adsorption capacity of MS for PO-P and MZ for NH-N was as high as 42.01 and 20.

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Article Synopsis
  • - KRAS mutations lead to aggressive tumors and drug resistance in colorectal cancer, making treatment difficult, particularly with targeted therapies like regorafenib.
  • - TRIM21, influenced by ERK2 and KRAS signaling, plays a key role in regulating c-Myc, which affects glycolysis and contributes to resistance to regorafenib.
  • - Targeting TRIM21 to inhibit its phosphorylation may improve treatments for KRAS-mutant colorectal cancer, with the antidepressant vilazodone showing promise in enhancing the effectiveness of regorafenib in research models.
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A composite wetland (CECW) was constructed by introducing P-adsorption filler (EPAF) and activated sludge into traditional wetlands for treating actual sewage. The results showed that EPAF improved P removal through physico-chemical adsorption, and it could be stably regenerated after adsorption saturation without potential risks. Meanwhile, zeolite promoted NH-N reduction in sewage by cation exchange.

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Cerebrovascular accidents, commonly known as strokes, represent a prevalent neurological event leading to significant upper limb disabilities, thereby profoundly affecting individuals' activities of daily living and diminishing their quality of life. Traditional rehabilitation methods for upper limb recovery post-stroke are often hindered by limitations, including therapist and patient fatigue, reliance on singular training methodologies, and lack of sustained motivation. Addressing these challenges, this study introduces an upper limb rehabilitation robot, which uses intelligent feedback motion control to improve therapeutic outcomes.

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Stroke rehabilitation often requires frequent and intensive therapy to improve functional recovery. Virtual reality (VR) technology has shown the potential to meet these demands by providing engaging and motivating therapy options. The digital occupational training system is a VR application that utilizes cutting-edge technologies, including multi-touch screens, virtual reality, and human-computer interaction, to offer diverse training techniques for advanced cognitive capacity and hand-eye coordination abilities.

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Non-noble metal catalysts are known for their efficient catalytic performance for oxygen reduction reaction (ORR), oxygen evolution reaction (OER), and hydrogen evolution reaction (HER). Metal organic gels (MOGs) can be considered as a promising electrocatalyst owing to the diverse physicochemical properties but usually suffer from its poor electrical conductivity and catalytic stability. Here, a FeCo-MOG is constructed with considerable trifunctional activity.

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Introduction: The use of mechanical ventilators in the intensive care unit (ICU) is often associated with higher risk of respiratory tract infections, including ventilator-associated pneumonia (VAP). Concomitant bacterial-viral infection was reported to worsen patient's clinical condition. This study evaluated the rate of concomitant bacterial-viral infections in patients with VAP and analyzed their clinical outcomes.

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To explore the appropriate controlled ovarian hyperstimulation (COH) protocols in infertility patients who received the fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatments during the COVID-19 pandemic. This retrospective cohort study evaluated the efficiency of the early follicular-phase long-acting GnRH-agonist long (EFLL) protocol (a new protocol developed by Chinese clinicians), prolonged pituitary down-regulation of EFLL protocol (Pro-EFLL), and the GnRH-ant protocol for couples meeting the study criteria between February 2020 and June 2020 who were treated by the First Affiliated Hospital of Zhengzhou University during the COVID-19 pandemic, and compared the pregnancy rates and miscarriage rates per fresh transfer cycle, number of retrieved oocytes, endometrial thickness on the day of hCG injection and the number of fertilized oocytes, mature oocytes, fertilized oocytes, and transferable embryos among the three protocols. We found that the prolonged pituitary down-regulation during the COVID-19 pandemic by utilizing a full-dose of GnRH-a administrated in infertility patients were no differences in clinical outcomes than other protocols, The prolonged pituitary down-regulation protocol and EFLL protocol were associated with a higher Endometrial thickness on the day of hCG injection (12.

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Article Synopsis
  • Chromosomal polymorphisms (CPMs) are typically harmless genetic variations, but some studies suggest they might be linked to reproductive issues, particularly in patients with chromosomal translocations (CT).
  • This study analyzed data from 26 patients with CPM and 56 controls with normal chromosomes, assessing fertilization and embryonic development metrics during preimplantation genetic testing between 2013 and 2019.
  • The findings indicated no significant differences in fertilization and cleavage rates between CPM and normal chromosomes; however, the high-quality blastocyst rate was notably lower for those with CTCPM compared to regular CT, suggesting that CPM may adversely affect embryo quality and development, especially in male carriers.
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The robot-assisted insertion surgery plays a crucial role in biopsy and therapy. This study focuses on determining the optimum puncture pattern for robot-assisted insertion, aiming at the matching problem of needle insertion parameters, thereby to reduce the pain for patients and to improve the reachability to the lesion point. First, a 6-degrees of freedom (DOFs) Computed Tomography (CT)-guided surgical robotic system for minimally invasive percutaneous lung is developed and used to perform puncture experiments.

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Background: Balanced complex chromosome rearrangements (BCCR) are balanced chromosomal structural aberrations that involve two or more chromosomes and at least three breakpoints. It is very rare in the population. The objective is to explore the difference of influence of three types of BCCR on early embryonic development and molecular karyotype.

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Background: Robot-assisted puncture has gradually attracted more attention and practical clinical application. The lesion positioning and the needle positioning are the basis to ensure the accuracy of puncture and the key techniques in insertion operation.

Methods: A lesion positioning method is established which is realized only by the robot-CT system without using external positioning system, and an omnidirectional needle positioning method is also developed and realized by using VRCM, in order to make the puncture needle always keep pointing to the lesion point.

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Background: The diverse medicinal properties of herbal compounds make them suitable candidates to treat multifactorial conditions such as pulmonary fibrosis. We investigated the effects and mechanisms of compound Chuanxiong Kangxian granules (CCKG) on a bleomycin (BLM)-induced pulmonary fibrosis model in rats.

Methods And Results: Following an intratracheal instillation of BLM, Sprague Dawley rats were intragastrically administrated with different doses of CCKG solution or hydrocortisone for 28 d, while control and BLM-treated rats were administered with saline solution.

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