Publications by authors named "Shi Tao Cui"
Background: The polymorphisms of VKORC1 and CYP2C9 play increasingly important roles in the inter-individual variability in warfarin dose. This study aimed to evaluate the feasibility of clinical application of pharmacogenetic-based warfarin-dosing algorithm in patients of Han nationality with rheumatic heart disease after valve replacement in a randomized and controlled trial.
Methods: One hundred and one consecutive patients of Han nationality with rheumatic heart disease undergoing valve surgery were enrolled and randomly assigned to an experimental group (n=50, based on CYP2C9 and VKORC1 genotypes, pharmacogenetic-based "predicted warfarin dose" for 3 days and then was adjusted to INR until stable warfarin maintenance dose) or a control group (n=51, 2.
Background: Vaspin was a recently identified adipokine, playing a protective role in many metabolic diseases. The present study aimed to investigate the association between vaspin plasma level and stable angina pectoris (SAP) and unstable angina pectoris (UAP).
Methods: A total of 88 patients with angiographically-proved coronary artery disease (CAD) (SAP 47, UAP 41) and 103 control subjects without cardiovascular diseases were enrolled in this study.
[Influence of advanced glycosylation end products on wound healing of burn rats with diabetes].
Zhonghua Shao Shang Za Zhi
December 2009
Article Synopsis
- - The study aimed to investigate how the accumulation of advanced glycosylation end products (AGE) affects wound healing in diabetic burn rats.
- - A total of 75 rats were divided into three groups (control, diabetes, and aminoguanidine-treated) and subjected to burn injuries; their wounds were monitored and tissue samples taken over 21 days.
- - Results showed that the diabetic rats had significantly slower wound healing compared to the control group, but those treated with aminoguanidine demonstrated improved healing rates and less glucose accumulation in the skin tissue.