Publications by authors named "Shi Lu"

The study aims to examine the association between disability status and willingness to share wearable devices and mobile apps data for public health research using the 2017 Behavioral risk Factor Surveillance System (BRFSS) through secondary data analysis. Current wearable device and mobile apps users at the time of the 2017 BRFSS survey administration from eight states were included in the analysis. Descriptive, chi-square analysis, and multivariable logistic regressions were performed to examine the associations.

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  • Breast milk is essential for infant nutrition, and specific Bifidobacterium strains can enhance health by utilizing human milk oligosaccharides (HMOs).
  • The study successfully isolated nine Bifidobacterium strains from breast milk, which demonstrated strong probiotic potential through various beneficial activities and safety profiles.
  • Notably, B. breve N-90 and B. infantis R-1 were identified as promising candidates for probiotic inclusion in simulated maternal milk formulas due to their effective utilization of HMOs and anti-inflammatory properties.
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Patch features obtained by fixed convolution kernel have become the main form in hyperspectral image (HSI) classification processing. However, the fixed convolution kernel limits the weight learning of channels, which results in the potential connections between pixels not being captured in patches, and seriously affects the classification performance. To tackle the above issues, we propose a novel Adaptive Pixel Attention Network, which can improve HSI classification by further mining the connections between pixels in patch features.

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Sodium ion capacitors (SICs) are promising candidates in energy storage for their remarkable power and energy density. However, the inherent disparity in dynamic behavior between the sluggish battery-type anodes and the rapid capacitor-type cathodes constrained their performance. To address this, we fabricated a hollow porous CoSe/ZnSe@MXene anode featuring multiheterostructure, utilizing facile etching and electrostatic self-assembly strategies.

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  • This study aimed to compare the effectiveness and safety of linezolid versus teicoplanin in treating hospital-acquired pneumonia (HAP) caused by Gram-positive bacteria in patients with renal issues.
  • The results showed that linezolid achieved a significantly higher bacterial eradication rate (88.5% vs 63.4%) but also led to more adverse reactions (42.0% vs 25.0%).
  • The optimal dosage strategy for linezolid was determined, recommending 300 mg every 12 hours for patients with better renal function and 200 mg for those with more severe renal insufficiency.
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Plant evolution is driven by key innovations of functional traits that enables their survivals in diverse ecological environments. However, plant adaptive evolution from land to atmospheric niches remains poorly understood. In this study, we use the epiphytic Tillandsioideae subfamily of Bromeliaceae as model plants to explore their origin, evolution and diversification.

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  • Mulberry leaf polysaccharides (MLP) show potential for treating Type 2 Diabetes Mellitus by reducing blood glucose and lipid levels, improving metabolism, and lowering insulin resistance in T2DM rats.
  • The study found that MLP helped restore gut microbiota balance by increasing beneficial bacteria like Prevotella, Ruminococcus, and Lactobacillus, which is crucial for gut health.
  • MLP also influenced bile acid metabolism by altering the expression of related enzymes and receptors, indicating a connection between gut microbiota and metabolic health in managing diabetes.
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A nomogram to estimate the risk of linezolid-induced thrombocytopenia in patients with renal impairment is not available. The aim of the study is to develop a nomogram for predicting linezolid-induced thrombocytopenia in patients with renal impairment and to investigate the incremental value of PNU-142300 concentration beyond clinical factors and linezolid trough concentration (C) for risk prediction. Logistic regression was used to identify independent risk factors for linezolid-induced thrombocytopenia in patients with renal impairment and nomograms were established.

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This study investigates the relationship among maternal secretor status, human milk oligosaccharides (HMOs), and the composition of breastmilk microbiota in a cohort of healthy mothers from Shaanxi province, China. The results demonstrated that 78.9% of the mothers were secretors, exhibiting an active fucosyltransferase 2 gene () and producing α-1,2 fucosylated HMOs, which significantly affected the HMO profile.

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Metal-organic frameworks (MOFs) are considered as potential solid-state electrolyte (SSE) materials due to their structural diversity and porosity. Adding lithium ions into the anionic frameworks of MOFs and then realizing single-ion transport is an efficient way to enhance the performance of ionic conductivity of SSE materials. Herein, an ionotropic MOF (Li[Cu-BTC]) with lithium ions in the pores of the lattice was synthesized through an ion exchange strategy, which exhibits outstanding lithium ionic conducting properties over a wide temperature range (ionic conductivity: 0.

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At present, tomato transplanting in facility agriculture is mainly manual operation. In an attempt to resolve the problems of high labor intensity and low efficiency of manual operation, this paper designs a clip stem automatic transplanting and seedling picking device based on the yolov5 algorithm. First of all, through the study of the characteristics of tomato seedlings of different seedling ages, the age of tomato seedlings suitable for transplanting was obtained.

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  • * Researchers have designed and synthesized a collection of 198 paracyclophane-based ionizable lipids (PILs) to improve mRNA delivery both in lab settings (in vitro) and in living organisms (in vivo).
  • * The optimized PIL LNPs show better performance than existing FDA-approved LNPs, indicating their potential for developing targeted mRNA therapies and vaccines, especially for liver-related treatments.
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Purpose: Bufalin (BU) is a bioactive ingredient extracted from the skin and parotid venom glands of Bufo raddei, which can effectively inhibit angiogenesis. The aim of this study was to investigate whether BU could affect corneal neovascularization (CoNV).

Methods: A rat CoNV model (right eye) was constructed by administration of NaOH, and the left eye served as a control.

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The underlying cellular diversity and heterogeneity from cervix precancerous lesions to cervical squamous cell carcinoma (CSCC) is investigated. Four single-cell datasets including normal tissues, normal adjacent tissues, precancerous lesions, and cervical tumors were integrated to perform disease stage analysis. Single-cell compositional data analysis (scCODA) was utilized to reveal the compositional changes of each cell type.

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Solid-state electrolytes (SSEs) based on metal-organic frameworks (MOFs) are an ideal material for constructing high-performance lithium metal batteries (LMBs). However, the low ion conductivity and poor interface contact (especially at low temperatures) still seriously hinder its further application. Herein, inspired by the Na/K conduction in biology systems, a series (NH, OH, NH-(CH)-SOH)-modified MIL-53-X as SSEs is reported.

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Leaf width is a key determinant of planting density and photosynthetic efficiency. In an effort to determine which genes regulate maize plant leaf width, we performed a genome-wide association study (GWAS) of 1.49 × 106 single nucleotide polymorphisms (SNPs) in 80 sequenced backbone inbred maize lines in Jilin Province, China, based upon phenotypic leaf width data from two years.

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Severe acute pancreatitis (SAP) is characterized by acute inflammation of the pancreas. The transcription factor BTB and CNC homology 1 (BACH1) has been implicated in various biological processes, including oxidative stress, apoptosis, and cell cycle regulation. However, its involvement in the pathogenesis of SAP remains relatively understudied.

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The aim of this study was to investigate whether the protective effect of 2-deoxyglucose (2-DG) on lung ischemia/reperfusion (I/R) injury is mediated by inhibiting nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)-mediated pyroptosis in rats. Male Sprague-Dawley rats were randomly divided into control group, 2-DG group, lung I/R injury group (I/R group) and 2-DG+I/R group. 2-DG (0.

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  • Researchers improved lipid nanoparticles (LNPs) for targeted mRNA delivery to specific organs, like the lungs and liver.
  • They created a library of new cationic lipids and optimized LNP compositions, finding that cholesterol and phospholipids are not essential for effectiveness.
  • This strategy enhances mRNA accumulation and translation in the target organs, potentially advancing mRNA therapy for various diseases.
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  • mRNA therapeutics have great potential for treating various diseases, but their use is limited due to instability and challenges in entering cells.
  • Lipid nanoparticles (LNPs) are the most common delivery systems for mRNA and gained attention after the success of COVID-19 mRNA vaccines.
  • The review discusses advancements in LNP technology, the roles of different lipid components, their applications, and future challenges in improving mRNA delivery systems.
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There is a lack of literature examining the engagement in strength activities of people with disabilities (PWD) using and not using wearable devices. The objectives of the current study were to determine the prevalence of strength activity engagement among wearable device users with disabilities, and to compare strength activity engagement between wearable device users and non-users with and without disabilities. Wearable device users and non-users with and without disabilities from eight states of the CDC's 2017 Behavioral Risk Factor Surveillance were included in the analysis.

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Background And Purpose: Intracranial hemorrhage (ICH) in leukemia patients progresses rapidly with high mortality. Limited data are available on imaging studies in this population. The study aims to develop prediction models for 7-day and short-term mortality risk based on the non-contrast computed tomography (NCCT) image features.

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Metal-organic frameworks (MOFs) have emerged as attractive candidates for Li conducting electrolytes due to their regular channels and controllable morphology, making their presence prominent in the field of solid-state lithium batteries. However, most MOF-based electrolytes are researched at or near room temperature, which poses a challenge to their practical applications at low temperatures. Herein, a thin layer flower-shaped 2D Cu-MOF (CuBDC-10)-based solid-state electrolytes (SSEs) for lithium-ion batteries (LIBs) are developed for facilitating Li transport at lower temperatures, which achieve an ion conductivity of 10 S cm at -30 °C.

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Background: Depression poses a major threat to public health with an increasing prevalence in the United States. Mindfulness-based interventions, such as mindfulness-based cognitive therapy (MBCT), are effective methods for managing depression symptoms and may help fortify existing efforts to address the current disease burden. The in-person group format of MBCT, however, incurs barriers to care such as expenses, childcare needs, and transportation issues.

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Purpose: Static magnetic fields (SMFs) induce various biological reactions and have been applied in the biological therapy of diseases, especially in combination with mesenchymal stem cells (MSCs) and tissue engineering. However, the underlying influence of SMFs on MSCs gene expression remains largely unclear. In this study, we aim to investigate the effects of SMFs on gene expression of human MSCs.

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