Reversible multivalent carrier redox exceeding intercalation capacity boundary.

Compared with widely established monovalent-ion batteries, aqueous multivalent-ion batteries promise higher capacity release by achieving multiple electron-transfer events per ion intercalation in the host material. Despite plausibility, this high-capacity dream is untenable with the total tolerable redox charge-transfer limit of the host material for all carrier species equally, which is historically assumed to depend on the material rather than the guest carrier itself, and the kinetic hysteresis induced by larger charge/radius ratios induced kinetic hysteresis further enlarges the divide. Herein, we report that copper carrier redox in vanadium sulfide (VS) exceeds the intrinsic intercalation capacity boundary, with the highest capacity release as 675 mAh g at 0.

Haplotyping-based preimplantation genetic testing for inherited cardiovascular disease: a multidisciplinary approach.

Given the high morbidity, mortality, and hereditary risk of cardiovascular diseases (CVDs), their prevention and control have garnered widespread attention and remain central to clinical research. This study aims to assess the feasibility and necessity of haplotyping-based preimplantation genetic testing for the prevention of inherited CVD. A total of 15 preimplantation genetic testing for monogenic defect (PGT-M) cycles were performed in 12 CVD families from January 2016 to July 2022.

Constructions, Purifications and Applications of DNA-Antibody Conjugates: A Review.

A DNA-antibody conjugate is a synthetic molecule that combines the unique functions of both an antibody and DNA. With the increased accessibility of commercialized kits, the procedure for constructing conjugates is simplified and the requirement for chemistry background is reduced. As a result, the difficulty of preparing a DNA-antibody conjugate has been significantly lowered.

Comprehensive analysis of chromosome abnormalities by chromosome conformation based karyotyping (C-MoKa) in patients with conception failure and pregnancy loss.

Background: Chromosome abnormalities are a leading cause of conception failure and pregnancy loss. While traditional cytogenetics technologies like karyotyping have been helpful in identifying structural variations (SVs), they face challenges in detecting complex rearrangements and cryptic structures. In this study, we developed a new method called chromosome conformation based karyotyping (C-MoKa) to comprehensively detect different types of chromosomal abnormalities in patients with conception failure and pregnancy loss.

Progress of AI assisted synthesis of polysaccharides-based hydrogel and their applications in biomedical field.

Polymeric hydrogels, characterized by their highly hydrophilic three-dimensional network structures, boast exceptional physical and chemical properties alongside high biocompatibility and biodegradability. These attributes make them indispensable in various biomedical applications such as drug delivery, tissue engineering, wound dressings and sensor technologies. With the integration of artificial intelligence (AI), hydrogels are undergoing significant transformations in design, leveraging human-machine interaction, machine learning, neural networks, and 3D/4D printing technology.

Design of a novel high-speed tensile method for testing the high strain rate tensile behavior of aluminum alloys.

The high-strain rate mechanical behavior of aluminum alloys is crucial for the stability of electromagnetic launch systems. However, current high-strain rate testing methods are not suitable for large-scale screening of materials needed in electromagnetic launch systems due to their low precision and high cost. In this paper, a novel method for high-strain rate tensile testing of aluminum alloys based on magnetic pulse driving was proposed.

Preparation, characterization, stability and functional properties of andrographolide loaded kafirin/carboxymethyl cellulose composite particles using antisolvent precipitation method.

Enhancing the oral bioavailability of hydrophobic nutraceuticals and protecting bioactive components through encapsulation systems has gained significant attention in food science. This study explored the preparation and characterization of kafirin (Kaf)/carboxymethyl cellulose (CMC) composite nanoparticles for encapsulating andrographolide (AG) using the antisolvent precipitation method. The optimal Kaf to CMC mass ratio was identified as 4:1, resulting in nanoparticles with an average diameter of 146.

Spatially Resolved CRISPR Screen Sequencing via Perturb-DBiT.

Perturb-seq enabled the profiling of transcriptional effects of genetic perturbations in single cells but lacks the ability to examine the impact on tissue environments. We present Perturb-DBiT for simultaneous co-sequencing of spatial transcriptome and guide RNAs (gRNAs) on the same tissue section for in vivo CRISPR screen with genome-scale gRNA libraries, offering a comprehensive understanding of how genetic modifications affect cellular behavior and tissue architecture. This platform supports a variety of delivery vectors, gRNA library sizes, and tissue preparations, along with two distinct gRNA capture methods, making it adaptable to a wide range of experimental setups.

O-band EML and 4-bits DAC enabled 112 GBaud PAM8 transmission over a 10 km SSMF without optical amplifiers.

The increasing traffic of intra-data center networks creates an urgent demand for low-cost and high-speed intensity modulation/direct detection (IM/DD) transmission. In this Letter, we propose a joint scheme combining nonlinear lookup table (NL-LUT) pre-distortion, digital pre-emphasis (DPE), and a digital resolution enhancer (DRE) to achieve high-speed and low-cost IM/DD optical links using a low-resolution digital-to-analog converter (DAC). The NL-LUT and DPE are responsible for the system nonlinear impairments and channel attenuation at high frequency, respectively, while DRE handles the quantization noise (QN) caused by high peak-to-average ratios (PAPRs) and low-resolution DAC.

RBD-EVIO: optimized event-based visual-inertial odometry for a large field of view with a rotated binary DART descriptor.

Event-based cameras offer unique advantages over traditional cameras, such as high dynamic range, absence of motion blur, and microsecond-level latency. This paper introduces an innovative approach to visual odometry, to our knowledge, by integrating the newly proposed Rotated Binary DART (RBD) descriptor within a Visual-Inertial Navigation System (VINS)-based event visual odometry framework. Our method leverages event optical flow and RBD for precise feature selection and matching, ensuring robust performance in dynamic environments.

Phase-locking-free all-optical matching system for 100 Gbaud QPSK optical signal.

Photonic firewall is a monitoring protection device that will directly detect and locate optical network attacks at the optical layer, which can effectively ensure the security of optical networks. An all-optical matching system is the core part of photonic firewall, which determines the performance of a photonic firewall, so it is of great significance to research and develop all-optical matching system for high-speed and high-order modulation formats signals. At present, an all-optical matching system for binary modulation formats is relatively mature, but the all-optical matching system for high-order phase modulation format signals is still limited by how to solve the problem of phase synchronization.

Precipitation versus dissolution at the phosphorus and Solanum nigrum L. root exudate interface: Implications for lead rebound in rhizosphere soils.

Lead (Pb) rebound in the root-zone of plants is a primary risk associated with rhizosphere effect in phosphorus (P)-amended vegetated soils. Herein, we investigated the differential effects of root exudates (RE) from Solanum nigrum L. on Pb availability under conditions with variable P mineral forms.

Contribution of cervical incompetence to occurrence of second trimester abortion in patients with polycystic ovary syndrome during the frozen embryo transfer cycle.

Background: Second-trimester abortion is a critical issue in infertile women with polycystic ovary syndrome (PCOS) treated with assisted reproductive technology (ART), cervical incompetence (CI) may play a role. Although previous studies have revealed an association between PCOS and CI in women undergoing ART with fresh embryo transfer, the associated risk factors in frozen embryo transfer cycles are still unknown. The primary objective of this study is to examine the impact of CI on the occurrence of second-trimester abortion in women with PCOS undergoing frozen embryo transfer.

Evaluation of Dexmedetomidine with Tiletamine-Zolazepam for Snow Leopard (Panthera uncia) Immobilization.

This study describes two different doses of dexmedetomidine combined with tiletamine-zolazepam (TZ) for anesthesia in snow leopards (Panthera uncia). A total of 11 adult snow leopards were anesthetized in Xining City, Qinghai Province, China from November 2019 to June 2023. We recorded the onset time, anesthesia duration, head-up time, and walking time.

Perspectives on NO Emissions and Impacts from Ammonia Combustion Processes.

Climate change and global warming necessitate the shift toward low-emission, carbon-free fuels. Although hydrogen boasts zero carbon content and high performance, its utilization is impeded by the complexities and costs involved in liquefaction, preservation, and transportation. Ammonia has emerged as a viable alternative that offers potential as a renewable energy storage medium and supports the global economy's decarbonization.

CRISPR screens unveil nutrient-dependent lysosomal and mitochondrial nodes impacting intestinal tissue-resident memory CD8 T cell formation.

Nutrient availability and organelle biology direct tissue homeostasis and cell fate, but how these processes orchestrate tissue immunity remains poorly defined. Here, using in vivo CRISPR-Cas9 screens, we uncovered organelle signaling and metabolic processes shaping CD8 tissue-resident memory T (T) cell development. T cells depended on mitochondrial translation and respiration.

Prepartum supplementation of dairy cows with inorganic selenium, organic selenium or rumen-protected choline does not affect carotenoid composition or colour characteristics of bovine colostrum or transition milk.

Minerals are supplemented routinely to dairy cows during the dry period to prevent metabolic issues postpartum. However, limited information exists on the impacts of mineral supplementation on colostrum carotenoids. This study aimed to determine the effects of prepartum supplementation with three micro-nutrients; inorganic selenium (INORG), organic selenium (ORG) or rumen-protected choline (RPC) on the carotenoid content of bovine colostrum and transition milk (TM) from pasture-based dairy cows.

CoBEV: Elevating Roadside 3D Object Detection with Depth and Height Complementarity.

Roadside camera-driven 3D object detection is a crucial task in intelligent transportation systems, which extends the perception range beyond the limitations of vision-centric vehicles and enhances road safety. While previous studies have limitations in using only depth or height information, we find both depth and height matter and they are in fact complementary. The depth feature encompasses precise geometric cues, whereas the height feature is primarily focused on distinguishing between various categories of height intervals, essentially providing semantic context.