Publications by authors named "Sheyuan Ding"
Marein ameliorates the progression of osteoarthritis: An in vitro and in vivo studies.
Int Immunopharmacol
January 2025
Osteoarthritis (OA) is a prevalent, degenerative joint disease that requires effective treatments to prevent its progression. Therefore, the development of novel therapeutic strategies to address this unmet clinical challenge is paramount. Marein (MA), the principal active compound of Coreopsis tinctoria Nutt, exhibits anti-inflammatory and anti-oxidant properties in various diseases, indicating its potential as a therapeutic agent for OA.
View Article and Find Full Text PDFGenetic Evidence of Obesity-Induced Chronic Wounds Mediated by Inflammatory Biomarkers.
Biol Res Nurs
November 2024
Article Synopsis
- - Patients with obesity are at a higher risk for skin diseases, especially chronic wounds, likely influenced by inflammatory biomarkers and genetic factors like SNPs.
- - A Mendelian Randomization study was conducted using genetic data from large biobanks to investigate how obesity affects chronic wounds through these inflammatory markers.
- - Results showed that obesity notably increases the risk of several types of ulcers, with specific biomarkers identified as mediators, suggesting avenues for potential treatments.