Predicting hypotension during anesthesia: Variation in pulse oximetry plethysmography predicts propofol-induced hypotension in children.

Background: The development of hypotension on administration of intravenous propofol is common and independently associated with adverse outcomes. Identifying patients with a high risk for anesthesia-induced hypotension may help anesthesiologists prepare for such an event.

Aim: The authors hypothesized that propofol-induced hypotension is predictable by variables related to fluid responsiveness and investigated such variables to determine the factors which can predict hypotensive events.

Comparison of remifentanil consumption in pupillometry-guided versus conventional administration in children: a randomized controlled trial.

Background: Remifentanil is a commonly used opioid analgesic during anesthesia in children. Objective measurement of pain is required for adequate dosing of remifentanil. We investigated whether pupillometry-guided remifentanil administration can reduce intraoperative consumption of remifentanil in children.

Microvolt T-wave alternans at the end of surgery is associated with postoperative mortality in cardiac surgery patients.

Microvolt T-wave alternans (MTWA), which reflects electrical dispersion of repolarization, is known to be associated with arrhythmia or sudden cardiac death in high risk patients. In this study we investigated the relationship between MTWA and postoperative mortality in 330 cardiac surgery patients. Electrocardiogram, official national data and electric chart were analysed to provide in-hospital and mid-term outcome.

The association between intraoperative urine output and postoperative acute kidney injury differs between partial and radical nephrectomy.

We sought to investigate the association between intraoperative urine output and postoperative acute kidney injury (AKI) in patients undergoing radical and partial nephrectomy. We retrospectively reviewed data of 742 patients. Postoperative AKI was defined by the Kidney Disease: Improving Global Outcomes criteria.

Intraoperative hyponatremia is an independent predictor of one-year mortality after liver transplantation.

Preoperative hyponatremia is associated with an increased risk of mortality on the liver transplantation (LT) waiting list. We sought to investigate the impact of pre- and intraoperative serum sodium levels on the one-year mortality after LT. We identified 1,164 patients for whom preoperative and intraoperative serum sodium levels were available.

Safety margin for needle placement during lumbar plexus block: An anatomical study using magnetic resonance imaging.

Purpose: We aimed to provide anatomic characteristics of the lumbar plexus and a safety margin for needle placement during lumbar plexus block in adults.

Methods: Lumbar spine magnetic resonance images from 377 adults were reviewed. We determined the depth of the lumbar plexus from the needle insertion point for the modified traditional and Capdevila's approaches at the L4 and L5 levels.

Comparison of rocuronium requirement in children with continuous infusion versus intermittent bolus: A randomised controlled trial.

Background: Minimising rocuronium administration during paediatric surgery helps to reduce the incidence of residual muscular blockade.

Objective: To determine whether intermittent bolus injection (Bolus group) or continuous infusion (group) requires the lesser amount of rocuronium.

Design: A randomised, single-blind controlled trial.

Pediatric Clinical Trials Conducted in South Korea from 2006 to 2015: An Analysis of the South Korean Clinical Research Information Service, US ClinicalTrials.gov and European Clinical Trials Registries.

Background: The status of pediatric clinical trials performed in South Korea in the last decade, including clinical trials of drugs with unapproved indications for children, has not been previously examined.

Objective: The aim was to provide information regarding the current state of pediatric clinical trials and create a basis for future trials performed in South Korea by reviewing three databases of clinical trials registrations.

Methods: We searched for pediatric clinical studies (participants <18 years old) conducted in South Korea between 2006 and 2015 registered on the Clinical Research Information Service (CRIS), ClinicalTrials.